Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II‐restricted CD4+ T cells upon immune‐complex uptake in vivo
JMH De Jong, DH Schuurhuis, A Ioan‐Facsinay… - …, 2006 - Wiley Online Library
… to acquire and present OVA-IC to OVA-specific CD4 + T cells in vivo. Our results revealed
that DC, but not macrophages or B cells are able to activate CD4 + T cells efficiently following …
that DC, but not macrophages or B cells are able to activate CD4 + T cells efficiently following …
[PDF][PDF] Dendritic cells, but not macrophages or B cells, activate MHC class II-restricted CD4 T cells upon immune-complex uptake in vivo.
JMH de Jong, DH Schuurhuis… - …, 2006 - scholarlypublications …
… the context of major histocompatibility complex (MHC) class II molecules. In contrast to MHC
… results revealed that DC, but not macrophages or B cells are able to activate CD4+ T cells …
… results revealed that DC, but not macrophages or B cells are able to activate CD4+ T cells …
Constitutive versus Activation-dependent Cross-Presentation of Immune Complexes by CD8+ and CD8− Dendritic Cells In Vivo
JMM den Haan, MJ Bevan - The Journal of experimental medicine, 2002 - rupress.org
… in vitro studies showed that DCs, but not macrophages, … capacity to stimulate OVA-specific
MHC class II–restricted OT-II cells: … that immune complex priming in the absence of both CD4 + …
MHC class II–restricted OT-II cells: … that immune complex priming in the absence of both CD4 + …
Fcγ receptor–mediated induction of dendritic cell maturation and major histocompatibility complex class I–restricted antigen presentation after immune complex …
… CD4 + helper and CD8 + cytotoxic T lymphocytes in vivo. … induces efficient MHC class II–restricted
presentation after IC … or cell activation, which are both efficient in macrophages or …
presentation after IC … or cell activation, which are both efficient in macrophages or …
Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
A Lanzavecchia - Annual review of immunology, 1990 - annualreviews.org
… In the case of gp120, CD4 + (but not CD8+) T cells are … , forming immune complex-coated
bodies (iccosomes), which are … , macrophages and professional APC are more likely than B …
bodies (iccosomes), which are … , macrophages and professional APC are more likely than B …
[HTML][HTML] Immune complex–mediated antigen presentation induces tumor immunity
K Rafiq, A Bergtold, R Clynes - The Journal of clinical …, 2002 - Am Soc Clin Investig
… MHC class II–restricted CD4 helper and MHC class I–restricted … phagocytosis, as previously
reported for macrophages (28). In … In our studies we show that DC uptake of ICs can directly …
reported for macrophages (28). In … In our studies we show that DC uptake of ICs can directly …
Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine
DH Schuurhuis, N van Montfoort… - The Journal of …, 2006 - journals.aai.org
… of CD4 + and CD8 + T cell responses and Ab responses in vivo. … II-restricted presentation
of Ag in vitro (11) and that IC-… cells are macrophages and NK cells, which can be activated …
of Ag in vitro (11) and that IC-… cells are macrophages and NK cells, which can be activated …
Accelerated antigen presentation and elicitation of humoral response in vivo by FcγRIIB-and FcγRI/III-mediated immune complex uptake
…, T Maeda, A Nakamura, K Akiyama, S Aiba, T Takai - Cellular …, 2003 - Elsevier
… and macrophages and primary epidermal Langerhans’ cells … on class II-restricted Ag
presentation both in vitro and in vivo for … measured by CD4 + T cells stimulated by DC that had …
presentation both in vitro and in vivo for … measured by CD4 + T cells stimulated by DC that had …
[HTML][HTML] Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells
… We investigated uptake of FVIII and FVIII immune complex by bone marrow … that DCs (but
not macrophages or B cells) activate MHC class II‐restricted memory CD4 + T cells in vivo after …
not macrophages or B cells) activate MHC class II‐restricted memory CD4 + T cells in vivo after …
Antigen presentation by dendritic cells for B cell activation
… To receive CD4 + T cell help, B cells must process and … SCS macrophages by cognate B
cells leads to B cell activation … ability of cDC2 over cDC1 to present MHC II-restricted antigens […
cells leads to B cell activation … ability of cDC2 over cDC1 to present MHC II-restricted antigens […