… adaptor protein MAVS is a target of DENV NS4A, revealing a novel function of the DENV NS4A
protein in modulating host innate immunity … pathological role in dengue diseases warrant …

… To establish infection in its host cells, DENV must subvert the … with mitochondrial antiviral
signaling protein (MAVS), which … evades the host immune system and suggest new targets for …

… over the signal to its adaptor proteins, which then recruit kinases … target the DNA-sensing
pathway to subvert innate immunity … signaling instead of targeting MAVS or STING directly (6). …

… -targeting chaperone protein 14-3-3ε Citation72 . NS4a will also inhibit RIG-I interaction with
MAVS by binding to the MAVS … virus targets the adaptor protein MITA to subvert host innate …

… MAVS interacts with the ER protein stimulator of interferon … in length, miRNAs inhibit translation
of target RNAs. Base-pair … In response, DENV subverts the innate antiviral responses by …

… its subsequent interaction with downstream adaptor protein MAVS, resulting in hindered
interferon … As explained above, DENV sfRNA targets innate immune signalling in human cells at …

… manipulate the innate immune responses of the host such as ‘… of RIG-I with the adaptor
protein MAVS by binding to the N-… The humoral immune system may also be directly subverted …

… Dengue virus (DENV) … host innate immune response. Herein, we examined the inhibitory
effects of DENV serotype 2 (DENV2) nonstructural proteins on RIG-I-directed antiviral immune …

… The protein expression of RIG-I and MAVS appeared to be similar in cells with WT or S135A-…
that MITA, a key adaptor molecule in host innate immune response, is targeted by the DEN …

… dengue fever to severe dengue (previously called dengue … of antiviral signaling via the
adaptor protein MAVS, which is … many viral pathogens to inhibit or subvert immune responses…