Determination of serum urea by mass fragmentography

I Björkhem, R Blomstrand, G Öhman - Clinica Chimica Acta, 1976 - Elsevier
… The reasons for conversion of urea into barbiturate prior to mass fragmentography in the
present work were the following: (1) Urea in itself is very difficult to analyze by gas …

Toward absolute methods in clinical chemistry: application of mass fragmentography to high-accuracy analyses.

I Björkhem, R Blomstrand, O Lantto… - Clinical …, 1976 - academic.oup.com
… reference methods based on mass fragmentography (specific ion monitoring) with use of
isotope-labeled internal standard, for determination of cholesterol, triglycerides, urea, glucose, …

Accuracy of some routine method used in clinical chemistry as judged by isotope dilution-mass spectrometry.

I Björkhem, A Bergman, O Falk, A Kallner… - Clinical …, 1981 - academic.oup.com
… of uric acid obtained with the massfragmentographicserum pool was prepared and the
concentrations of cholesterol, creatinine, uric acid, urea, glucose, and cortisol were determined

Measurement of urea in human serum by isotope dilution mass spectrometry: a reference procedure

A Kessler, L Siekmann - Clinical Chemistry, 1999 - academic.oup.com
… In the present investigation, a reference measurement procedure for the determination of
urea in serum based on the principle of ID-MS is described. The combination of GC/MS and ID …

GC-MS determination of ratios of stable-isotope labelled to natural urea using [13C15N2] urea for studying urea kinetics in serum and as a means to validate routine …

BG Wolthers, T Tepper, A Withag, GT Nagel… - Clinica chimica acta, 1994 - Elsevier
… from 100 to 300 amu Mass fragmentography of urea was performed in the EI mode by
monitoring mass fra~ents de = 153 (natural urea) and m/e = 156 (labelled urea) and calculation (…

Use of isotope dilution—mass spectrometry for accuracy control of different routine methods used in clinical chemistry

I Björkhem, R Blomstrand, S Eriksson… - … Journal of Clinical …, 1980 - Taylor & Francis
… Isotope dilution mass fragmentography is an analytical technique with a relatively … serum
pool was prepared and the concentration determined of cholesterol, creatinine, uric acid, urea

A gas chromatographic-mass spectrometric assay for nine hydroxyphenolic acids in uremic serum

N Toshimitsu, O Toyokazu, M Kenji, S Akira… - Clinica Chimica …, 1979 - Elsevier
… A mass fragmentographic method for the determination of m-hydroxybenzoic acid, p-…
Statistical analysis between normal and uremic group could not be done, because the levels of the …

Determination of pipecolic acid in urine and plasma by isotope dilution mass fragmentography

GA van den Berg, H Breukelman, H Elzinga… - Clinica Chimica …, 1986 - Elsevier
mass spectrometric detection for the determination of pipecolic acid in urine and plasma (or
serum)… compound was tentatively identified as some heptafluorobutyrated derivative of urea. …

Blood urea nitrogen and creatinine

JL Lyman - Emergency medicine clinics of North America, 1986 - Elsevier
… A newer method involves the analysis of creatinine-containing fluids via gas chromatography
and mass spectrometry, called the mass fragmentographic process. All of the methods …

Measurement of antidiabetic sulfonylureas in serum by gas chromatography with electron-capture detection

WE Braselton Jr, ED Bransome Jr, TA Huff - Diabetes, 1977 - Am Diabetes Assoc
mass fragmentography was used only to validate the simpler, more generally applicable
procedure of EC-GLC. Since the mass fragmentography … drug and not on blank serum to which …