… for differences in drug absorption and disposition during development. Therefore, due to
different absorption, distribution, metabolism or excretion of a given drug at different ages, the …

… testinal absorption of xenobiotics was thought to be similar between species. … as differences
in excretion itself, may be responsible for species differences in the elimination of xenobiotics…

… Mice showed no difference between absorption of biliary excreted 203Pb and of 203Pb
administered into duodenum in rats without cannulation of the bile duct. Presence of bile …

… body is the difference between the amount absorbed and the … This relationship between rate
of metabolism and enzyme … of the xenobiotic is sufficient to saturate the elimination enzymes…

… of xenobiotic-metabolizing enzymes may be quite different in … , xenobiotics and their metabolites
are also excreted from the … route of elimination for chemicals that are well absorbed and …

… II conjugation of xenobiotics, including variations present in the … xenobiotics and their
metabolites are eliminated from the … of xenobiotic pharmacokinetics—absorption, distribution, …

… affects their distribution, metabolism, and elimination. … drug metabolism by a mechanism
that is different from the other … similar rates of uptake and clearance of a xenobiotic. Chemicals …

… absorption, distribution, excretion and the rate and pattern of … species, (3) a comparison of
man and his near neighbours … far away is the rat from man in the metabolism of xenobiotics. …

… on skin metabolism as it pertains to dermal absorption, in … to distinguish cutaneous from
systemic metabolic processes, … the systemic distribution and elimination are estimated from …

… differences in xenobiotic metabolism exist in … metabolism and elimination of xenobiotics,
the levels and composition of isoforms of renal cytochromes P450 may be very important from a …