Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology
S Le Corre, D Eyre, IA Drummond - Journal of the American …, 2014 - journals.lww.com
… treatment of autosomal dominant polycystic kidney disease. Autosomal dominant polycystic
kidney disease (ADPKD) is the most common heritable human disease, with an incidence of …
kidney disease (ADPKD) is the most common heritable human disease, with an incidence of …
Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins
Y Huan, J van Adelsberg - The Journal of clinical …, 1999 - Am Soc Clin Investig
… , we stained sections of fetal kidney with antibodies to polycystin-… β-catenin, we examined
the distribution of actin within the … renal epithelial cells develop fatal polycystic kidney disease, …
the distribution of actin within the … renal epithelial cells develop fatal polycystic kidney disease, …
Dysplastic and polycystic kidneys: diagnosis, associations and management
P Winyard, L Chitty - … Diagnosis: Published in Affiliation With the …, 2001 - Wiley Online Library
… maturation are observed in polycystic kidney disease (PKD). … is unremarkable in these
kidneys, but there is later cystic dilation of … Distribution of alpha-integrin subunits in fetal polycystic …
kidneys, but there is later cystic dilation of … Distribution of alpha-integrin subunits in fetal polycystic …
Strategies targeting cAMP signaling in the treatment of polycystic kidney disease
VE Torres, PC Harris - Journal of the American Society of …, 2014 - journals.lww.com
Polycystic kidney disease (PKD) is a leading cause of ESRD worldwide. In PKD, excessive
cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with …
cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with …
[HTML][HTML] Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling
X Zhou, VE Torres - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
… specific expression of constitutively active AMPK, with a gain-of-function mutation in the
AMPKγ1 subunit, resulted in an early-onset polycystic kidney phenotype with collecting duct cysts…
AMPKγ1 subunit, resulted in an early-onset polycystic kidney phenotype with collecting duct cysts…
Renal cystic disease
F Hildebrandt - Current Opinion in Pediatrics, 1999 - journals.lww.com
… polycystic kidney disease Autosomal recessive polycystic … Age at diagnosis was distributed
over the different age groups … two fetuses who presented with enlarged, hyperechoic kidneys …
over the different age groups … two fetuses who presented with enlarged, hyperechoic kidneys …
Analysis of inversin in mouse kidney and cultured renal epithelial cells
HH Ward - 2007 - search.proquest.com
… cystic kidneys. However, ICKD phenotypes differ by age of onset of cystic kidney disease
(CKD), cyst location within the kidney… that the subcellular distribution of inversin isoforms is …
(CKD), cyst location within the kidney… that the subcellular distribution of inversin isoforms is …
[HTML][HTML] Expression of mitogen-activated protein kinases in human renal dysplasia
S Omori, R Fukuzawa, M Hida, M Awazu - Kidney international, 2002 - Elsevier
… Dysplastic and control kidneys were obtained from fetuses of spontaneous miscarriages
and abortions … Distribution of proliferating cells and apoptosis in normal and dysplastic …
and abortions … Distribution of proliferating cells and apoptosis in normal and dysplastic …
Use of adhesion molecules for gene delivery
S Hart - Nephron Experimental Nephrology, 1999 - karger.com
… as fusions with pIII, a minor coat protein subunit present in four or five copies at one end of
… 47 van Adelsberg J: Murine polycystic kidney epithelial cell lines have increased integrin-me…
… 47 van Adelsberg J: Murine polycystic kidney epithelial cell lines have increased integrin-me…
Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation
MF Horster, GS Braun, SM Huber - Physiological reviews, 1999 - journals.physiology.org
… abnormalities such as cystic kidney and undifferentiated … the primary event is a regulated
breakdown of DNA into small, … and AQP2 were localized in human fetal kidney (46). Both …
breakdown of DNA into small, … and AQP2 were localized in human fetal kidney (46). Both …