… Androgen-receptor antagonists (bicalutamide, flutamide) are … into dysplasia/prostatic
intraepithelial neoplasia and finally … these trials, a phase 2 randomized placebo-controlled trial of …

… , randomized, double blind, placebo-controlled clinical trial … Therefore, the combination of
cancer chemoprevention, PSA … Finally, tumor volume and prostatic intraepithelial neoplasia (…

… histologic changes in prostatic intraepithelial neoplasia (PIN) … the recommended dose of the
antiandrogen flutamide (125 mg, 3 … : a randomized, double-blind, placebo-controlled study. …

… chemoprevention of prostate cancer. Because high-grade prostatic intra-epithelial neoplasia
… , 1 treated with diethylstilbestrol along with leuprolide and flutamide, and three treated with …

… – results of a prospective randomized placebo controlled study [abstract… Flutamide in men
with prostatic intraepithelial neoplasia: a randomized, placebo-controlled chemoprevention trial…

… Both flutamide and toremifene decreased the tumour incidence, … A 1-year, double-blind,
placebo-controlled proof-ofprinciple study … with highgrade prostate intraepithelial neoplasia: a …

… Chemoprevention, prostate-specific antigen (PSA) … study used toremifene at a dose of 20
to 60 mg to prevent PC incidence in men with high-grade prostatic intraepithelial neoplasia (…

… via prostatic intraepithelial neoplasia grade I–III to manifest … or castration plus flutamide
(withdrawal of flutamide due to side … A placebo-controlled, randomized study has been initiated to …

… combination with flutamide, on prostatic intraepithelial neoplasia (… first phase 3 (randomized,
placebo-controlled, prospective) … In this trial, 18,882 men were randomized to receive either …

… , and survival of prostatic epithelial cells, although some of … -blind randomized study to
compare the efficacy of flutamide … therapy is used for prostate cancer chemoprevention. Target …