Characteristics of in vivo model systems for ovarian cancer studies

P Tudrej, KA Kujawa, AJ Cortez, KM Lisowska - Diagnostics, 2019 - mdpi.com
… of animal models available for basic and preclinical studies. … cells’ tumorigenicity, tumor
histology, and for testing of tumor … origin of ovarian cancers, genetic events necessary for tumor

Epithelial ovarian cancer experimental models

E Lengyel, JE Burdette, HA Kenny, D Matei, J Pilrose… - Oncogene, 2014 - nature.com
… currently available genetic mouse models of OvCa, the … from the ovarian tumor of a patient
with stage III human ovariantumors with a histology that is also very similar to a human serous …

Histology of the Ovary of the Laying Hen (Gallus domesticus)

KD Apperson, KE Bird, G Cherian, CV Löhr - Veterinary Sciences, 2017 - mdpi.com
… Epithelial ovarian cancer in other animal models is usually induced experimentally or by …
in the ovarian surface epithelium of laying hens and women while ovarian tumors of other …

Genistein prevents development of spontaneous ovarian cancer and inhibits tumor growth in hen model

K Sahin, E Yenice, B Bilir, C Orhan, M Tuzcu… - Cancer Prevention …, 2019 - AACR
models and the dissimilarities in the histopathology of ovarian cancer between mouse and
humanovarian cells in both hen and human ovarian cancers (47). Histologic classification of …

… -targeted ultrasound imaging agent enhances the detection of ovarian tumors at early stage in laying hens, a preclinical model of spontaneous ovarian cancer

A Barua, A Yellapa, JM Bahr, SA Machado… - Ultrasonic …, 2015 - journals.sagepub.com
… Spontaneous incidence of OVCA with histopathology and … ovarian tumors in laying hens,
a preclinical model of OVCA. Enhancement of visualization of spontaneous ovarian tumors was …

Novel approach to optimize the Laying Hen Model of ovarian cancer

SJ Gillenwater - 2017 - oaktrust.library.tamu.edu
laying hens, though not fully characterized, could be an optimal animal model for the study
of human ovarian cancer … metastatic cancer based on histopathology was ovarian carcinoma

Polycystic ovarian condition may be a risk factor for ovarian tumor development in the laying hen model of spontaneous ovarian cancer

HJ Lee, JM Bahr, P Bitterman, S Basu… - Journal of …, 2018 - Wiley Online Library
… , laying hens develop OVCA spontaneously, and the histopathology of ovarian tumors as …
incidence of polycystic ovarian condition in laying hens, a preclinical model of spontaneous …

Contrast‐Enhanced Sonography Depicts Spontaneous Ovarian Cancer at Early Stages in a Preclinical Animal Model

A Barua, P Bitterman, JM Bahr, S Basu… - … of Ultrasound in …, 2011 - Wiley Online Library
laying hens, a preclinical model of human spontaneous … histopathologic characteristics 22
and expression of several cellular and molecular makers common to human ovarian tumors. …

A review of principal studies on the development and treatment of epithelial ovarian cancer in the laying hen Gallus gallus

P Pal, KN Starkweather, KH Hales… - Comparative …, 2021 - ingentaconnect.com
… While developing a reliable animal model is challenging due … , laying hens naturally develop
EOC that is histopathologically … about 90% of ovarian tumors in laying hens express CA125,…

Association of interleukin 16 with the development of ovarian tumor and tumor-associated neoangiogenesis in laying hen model of spontaneous ovarian cancer

A Yellapa, JM Bahr, P Bitterman… - … of Gynecologic Cancer, 2012 - ijgc.bmj.com
… the association of IL-16 with tumor development and ovarian TAN in laying hens, an …
Histopathology of ovarian tumors in laying hens: a preclinical model of human ovarian cancer