… ovarian carcinoma is still far from optimal, animal models are still needed to study human
epithelial ovarian cancer… International journal of clinical and experimental pathology. 2012;5(1):…

… events at the basis of ovarian carcinoma. The genetically engineered … In one study 16 155
young and old laying hens were … These lesions met all the histopathological criteria for human …

… Animal models of ovarian cancer can shed light on the genetic … 1) to further characterize
chicken ovarian tumors through global … Normal hens (n=3) showed no gross or histopathological …

… laying hen {Gallus domesticus) as a model of ovarian cancer since tumors occur naturally,
their histology … integrates with ovarian tumor progression in a spontaneous animal model. …

… mutations play in establishing ovarian tumors. Many of these … , the oviduct, and uterus
generated endometrioid histology … 2) (as well as other animal models, such as the laying hen) 53 …

… The domestic fowl has great potential as an animal model for ovarian cancer research,
with … the possibility that chicken and human ovarian cancers have a common pathogenesis …

… hen as an animal model for the study of ovarian cancer. The hen is the only the only animal
model in … and histopathological phenotype of ovarian carcinoma in the aging White Leghorn …

… as a suitable animal model for investigating the … Ovarian cancer is prevalent in hens that
are more than 2 years old and cannot produce eggs. To efficiently obtain chicken ovarian tumor …

… hens have a greater incidence of ovarian neoplasms than do Key words: ovarian cancer,
hen, animal model, … The tumors that resulted in this transgenic mouse model were stromal in …

… complement to mouse model systems to study human disease. … ), disease progression,
histology, and molecular genetics, … the hen gene expression model of ovarian cancer and to test …