… has been limited by the lack of suitable animal models. The … in ovarian tumors to 6-fold
compared to normal ovaries. MSX2… mRNA in normal ovaries in the absence of pathology. That all …

… 60% (6/10) of hens with ovarian tumors. Conclusion: MSLN gene and … ovarian tumors and
not detectable in normal ovaries. The results support the utility of the hen model for preclinical …

… The hen is an attractive animal model for in vivo testing of … model suitable to study
epithelial ovarian carcinoma … The gross pathology of mortalities in the present study reveals …

… Ovarian neoplasms were verified based on histology. … survival in a mouse model of the
disease (37). Although we did not directly measure tumor onset in this study, hens treated with …

… breast and prostate tumours, its value in ovarian tumours is still … Mouse tumours originating
from the surface epithelium are … of hens are remarkably good replicas of their human tumour …

… of ovarian cancer were determined by gross pathology and … the laying hen (Gallus domesticus)
as an animal model for the … of total ovarian cancers between the flaxseed-fed hens (24%) …

… the ovary changes in response to spontaneous ovarian tumor … as radiotherapies, this animal
model of spontaneous OVCA … model resembles human OVCA in histopathology and tumor …

… hen (Gallus gallus domesticus) to study the molecular mechanisms involved in the development
of ovarian carcinoma in humans … the etiology of the human pathology is still undefined, …

… the hen, an animal model of spontaneous human ovarian cancer, … tumor ovary structures
was based on our prior studies of ovarian tumor histology [23] and immune cells [24] in the hen. …

… The domestic laying hen is a useful model for human ovarian carcinoma for many reasons.
Adult female animals of most species, whether domestic or wild, are either persistently …