Designing In Vitro Strategies and In Vivo Models for Alzheimer's Disease-Promises & Challenges

P Kumaraswamy, S Sethuraman… - Current Alzheimer …, 2014 - ingentaconnect.com
… proteins present in the human of which 36 are associated with the diseased conditions [38].
Among this 26 different proteins have been identified and biochemically characterized as the …

Role of imaging in the era of precision medicine

A Giardino, S Gupta, E Olson, K Sepulveda… - Academic radiology, 2017 - Elsevier
… the challenges for radiology in the era of precision medicine. … shows great promise in the era
of precision medicine. Recent … of biological processes at the molecular and cellular levels in …

Biomedical application of immobilized enzymes

JF Liang, YT Li, VC Yang - Journal of pharmaceutical sciences, 2000 - Elsevier
… in immobilized enzyme use in medicine. Generally speaking, … difficulties when operating
in vivo or in undiluted biological … Like RBCs, liposomes can also fulfill the promise of a drug‐…

Skin-interfaced wearable sweat sensors for precision medicine

J Min, J Tu, C Xu, H Lukas, S Shin, Y Yang… - Chemical …, 2023 - ACS Publications
… the promise of providing noninvasive and continuous insight into the biochemical landscape
… case of burn victims presents new challenges in regenerative wound healing and demands …

Bench to bedside molecular functional imaging in translational cancer medicine: to image or to imagine?

A Mahajan, V Goh, S Basu, R Vaish, AJ Weeks… - Clinical radiology, 2015 - Elsevier
… (MRI) for studying in vivo biological changes related to … -choline and other choline
analogues, such as 18 F-choline, … This has shown promise in detecting primary prostate cancer …

Microenvironment-driven intratumoral heterogeneity in head and neck cancers: clinical challenges and opportunities for precision medicine

H Zaryouh, M Vara-Messler, J Vignau… - Drug Resistance …, 2022 - Elsevier
… for which treatment remains a clinical challenge. Indeed, despite aggressive multimodal …
patients who progress after these treatments (unmet medical need). The lack of significant …

Oral delivery of biologics for precision medicine

M Durán‐Lobato, Z Niu, MJ Alonso - Advanced Materials, 2020 - Wiley Online Library
… design, aiming at confronting each of the biological barriers. The elucidation of their multi-step
mechanism of interaction with the intestinal epithelium opens up new exciting challenges. …

Kinetic and Structural Studies on Flavin-dependent Enzymes involved in Glycine Betaine Biosynthesis and Propionate 3-nitronate Detoxification

F Salvi - 2015 - scholarworks.gsu.edu
… of human choline dehydrogenase were carried out and a homology model based on choline
… in distinct classes is a difficult challenge. Furthermore, flavoproteins sometime are more …

Milk-Derived Extracellular Vesicles: Biomedical Applications, Current Challenges, and Future Perspectives

M Salehi, B Negahdari, F Mehryab… - Journal of Agricultural …, 2024 - ACS Publications
… their challenges and enormous promise as a novel class of theranostics. It is hoped that this
study will pave the way for clinical applications of miEVs by addressing their challenges and …

Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
… , shows great promise in identifying diagnostic markers for thyroid lesions. … biological
processes but also opening up new avenues for research in fields such as personalised medicine, …