Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of asthma
… Aim of the Study: MicroRNA-21 (miR-21) is up-regulated during allergic airway inflammation,
… of an miR-21 antagomir and its mechanism of action in a mouse model of acute bronchial …
… of an miR-21 antagomir and its mechanism of action in a mouse model of acute bronchial …
[HTML][HTML] MicroRNA-21 inhibition suppresses alveolar M2 macrophages in an ovalbumin-induced allergic asthma mice model
… M2 macrophage inhalation restored AHR and eosinophilic airway inflammation in the
miR-21 antagomir-treated mice. Moreover, anti-miR-21 antagomir transfection decreased the …
miR-21 antagomir-treated mice. Moreover, anti-miR-21 antagomir transfection decreased the …
[HTML][HTML] MicroRNA-21 inhibition attenuates airway inflammation and remodelling by modulating the transforming growth factor β–Smad7 pathway
J Hur, CK Rhee, SY Lee, YK Kim… - The Korean Journal of …, 2021 - ncbi.nlm.nih.gov
… inhibition attenuated airway inflammation and airway remodelling in this mouse model of
OVA-induced chronic allergic … chronic asthma model that inhibition of miR-126 by antagomir did …
OVA-induced chronic allergic … chronic asthma model that inhibition of miR-126 by antagomir did …
[HTML][HTML] The relevance of miRNA-21 in HSV-induced inflammation in a mouse model
B Choi, HA Kim, CH Suh, HO Byun, JY Jung… - International journal of …, 2015 - mdpi.com
… between microRNA-21 (miR-21) expression and inflammation … In this study, antagomir-mediated
inhibition of miR-21 was … that colchicine or pentoxifylline treatment ameliorated BD-like …
inhibition of miR-21 was … that colchicine or pentoxifylline treatment ameliorated BD-like …
[HTML][HTML] MicroRNA-21 released from mast cells-derived extracellular vesicles drives asthma in mice by potentiating airway inflammation and oxidative stress
Y Zou, Q Zhou, Y Zhang - American journal of translational …, 2021 - ncbi.nlm.nih.gov
… of the asthma mouse model, we stained the lung tissues of the mice using HE staining, …
Finally, we identified the effects of miR-21 and DDAH1 inhibition on asthmatic mice by HE …
Finally, we identified the effects of miR-21 and DDAH1 inhibition on asthmatic mice by HE …
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
… exposed mice were treated with a miR-21–specific antagomir… CS exposure reduced
lung SATB1 in a mouse model of COPD, … was inhibited with an miR-21–specific inhibitor (antagomir, …
lung SATB1 in a mouse model of COPD, … was inhibited with an miR-21–specific inhibitor (antagomir, …
MicroRNAs: potential biomarkers and targets of therapy in allergic diseases?
K Specjalski, E Jassem - Archivum immunologiae et therapiae …, 2019 - Springer
… both animal models and human studies on asthma and allergic rhinitis. On the contrary, their
increased levels inhibit the expression of various inflammatory … led to amelioration of rhinitis …
increased levels inhibit the expression of various inflammatory … led to amelioration of rhinitis …
[HTML][HTML] miR-21 silencing ameliorates experimental autoimmune encephalomyelitis by promoting the differentiation of IL-10-producing B cells
H Wang, W Xu, Q Shao, Q Ding - Oncotarget, 2017 - ncbi.nlm.nih.gov
… Here, we found that microRNA-21 (miR-21) acts as an … in a mouse model of lupus [8].
Moreover, miR-21-knockout … of EAE in antagomiR-21-treated mice was mainly induced by …
Moreover, miR-21-knockout … of EAE in antagomiR-21-treated mice was mainly induced by …
MicroRNA: potential biomarkers and therapeutic targets for allergic asthma?
HL Tay, M Plank, A Collison, J Mattes… - Annals of …, 2014 - Taylor & Francis
… For example, in a murine model of the onset of allergic asthma in … Importantly, this study
demonstrated that inhibition of a … treatment as a novel therapy, we compared antagomir treatment …
demonstrated that inhibition of a … treatment as a novel therapy, we compared antagomir treatment …
MicroRNA-21-5p promotes mucosal type 2 inflammation via regulating GLP1R/IL-33 signaling in chronic rhinosinusitis with nasal polyps
G Luan, M Wang, J Yuan, X Bu, Y Wang, S Ying… - Journal of Allergy and …, 2022 - Elsevier
… The eosinophilic CRSwNP murine model used in the present … antagomir could suppress
the development of allergic airway … asthma model, miR-21 inhibitor–treated mice had both anti-…
the development of allergic airway … asthma model, miR-21 inhibitor–treated mice had both anti-…