… VEGF receptors (VEGFRs) by VEGF family members in skeletal muscle, we develop a
computational model of VEGF isoforms (VEGF 121 , VEGF … extracellular matrix in in vivo tissue. We …

… a computational model of the interactions between NRP1 and … complexes by the isoforms
VEGF 121 and VEGF 165 . We … computational models of endothelial cell behavior in in vitro …

… Additionally, our model predicts that VEGF isoform-specific … -specific phosphorylation in
vivo, mediated by Neuropilin-1. … similar to that for VEGF, as both interactions occur via heparin-…

… release regulate VEGF diffusion in vivo are therefore not yet … VEGF isoforms also differentially
bind to neuropilin-1 and -2 (… 2 primarily details the interactions of secreted VEGF 165 , we …

… bioavailability and interaction with the co-receptor Neuropilin-1. … both in vitro and in vivo
experimental evidence, VEGF xxx a … Computational modelling of systems pharmacology have …

… Using an in vitro binding assay, we have determined the … arginine is essential for the
interaction of VEGF-A with Nrp1 and … For example, VEGF-A binds to VEGFR-1 and VEGFR-2, but …

… isoforms of vascular endothelial growth factor A (VEGF-A) can bind to the receptor tyrosine
kinases VEGFR-1 and VEGFR-2… cells in vitro suggests that these components are interacting (…

… , and co-receptors Neuropilin-1 and Neuropilin-2. We utilize … interactions of two VEGF isoforms
(VEGF 121 and VEGF 165 )… Still, our computational studies complement the experimental …

… predict that VEGF immobilization, interactions with Neuropilin-1, … only VEGF 188 or modified
protease-resistant VEGF isoforms … We developed a model to simulate in vitro experiments in …

… In the present study, we extend the previous computational model … The molecular interactions
between the VEGF isoforms and … in the effect of neuropilin density, as only in vitro data are …