Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

J M. Johnston, W T. Hu, D W. Fardo… - Current Alzheimer …, 2014 - benthamdirect.com
… at baseline with plasma leptin data. Herein we show gender differences in leptin levels of NC
… cases, with approximately twofold higher levels of leptin in women compared to men. More …

Impact of serum leptin and adiponectin levels on brain infarcts in patients with mild cognitive impairment and Alzheimer's disease: a longitudinal analysis

G Carbone, L Bencivenga, MA Santoro… - Frontiers in …, 2024 - frontiersin.org
… The cohort of subjects extracted from ADNI database for this study … with serum leptin levels
in our population were age, gender, BMI, … differ among the three diagnostic groups. However, …

Plasma leptin is associated with amyloid CSF biomarkers and Alzheimer's disease diagnosis in cognitively impaired patients

M Lilamand, E Bouaziz-Amar… - The Journals of …, 2023 - academic.oup.com
plasma leptin levels and the diagnostic groups, with regard to the stage of … , leptin levels
were strongly influenced by gender and body composition, and we observed gender differences

Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment

R Oania, LK McEvoy - Age and ageing, 2014 - academic.oup.com
… The criteria for a diagnosis of MCI included Mini-Mental State Exam score between 24 and
30, … We downloaded the quality-controlled plasma measures from the public ADNI website. As …

Plasma leptin levels and free leptin index in women with Alzheimer's disease

A Baranowska-Bik, W Bik, M Styczynska… - Neuropeptides, 2015 - Elsevier
… Previously, gender dimorphism of peripheral leptin … The diagnosis of AD was established
according to the NINCDS-… confirmed a decrease in plasma leptin levels in subjects with AD. …

Obesity as a Risk Factor for Alzheimer's Disease: The Role of Adiponectin

LRV Letra - 2018 - search.proquest.com
… and leptin among Mild cognitive impairment (MCI) and Alzheimer’s dementia (AD) subjects.
… , and the assignment of different degrees of likelihood of diagnosis to clinical syndromes of …

Nonobese male patients with Alzheimer's Disease are vulnerable to decrease in plasma leptin

J Tian, T Wang, K Jia, L Guo… - Journal of Alzheimer's …, 2022 - content.iospress.com
… a therapeutic potential of leptin-boosting agents for the … in plasma leptin levels in females
regardless of AD diagnosis, … sex-related leptin regulation in AD patients and subjects at risk …

Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly

P Rajagopalan, AW Toga, CR Jack, MW Weiner… - …, 2013 - journals.lww.com
plasma leptin in the full ADNI group and the MCI group of individuals, regardless of their
diagnosis or BMI, possibly track the effects of leptinleptin levels in the plasma, and the potential

The role of leptin and adiponectin in obesity-associated cognitive decline and Alzheimer's disease

L Forny-Germano, FG De Felice… - Frontiers in …, 2019 - frontiersin.org
… disorders may prove of major relevance to diagnostic, prevention and therapy. … of leptin in
the brain are subject to regulation by local leptin production, circulating leptin levels and leptin

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

S Maioli, M Lodeiro, P Merino‐Serrais, F Falahati… - Aging cell, 2015 - Wiley Online Library
… no significant differences between the four diagnostic groups (… leptin levels in the CSF of 278
subjects from the ADNI cohort. … difference observed is probably due to gender differences in …