Mast cell degranulation mediates compound 48/80-induced hyperalgesia in mice

D Chatterjea, A Wetzel, M Mack, C Engblom… - Biochemical and …, 2012 - Elsevier
mast cells produced plantar hyperalgesia in mice. Basic secretagogue compound 48/80
induced plantar mast cell degranulation accompanied by thermal hyperalgesia, tissue edema, …

Evidence for the modulation of nociception in mice by central mast cells

CL Kissel, KJ Kovács, AA Larson - European Journal of Pain, 2017 - Wiley Online Library
… For example, all formalin-induced responses are centrally mediated, as indicated by the
ability of opioid compounds to inhibit both Phase I and Phase II responses. However, Phase I …

The Comparison of Effects of Applications of Compound 48/80 and Mast Cell Mediator Suspension on Inflammation in Rats: A Methodological Study for Acute …

E Kilinc, Y Dagistan, A Cetinkaya… - Clinical and Experimental …, 2019 - dergipark.org.tr
Compound 48/80-induced degranulation of mast cells in the dura mater in compound 48/80 …
Mast cell degranulation mediates compound 48/80-induced meningeal vasodilatation …

[HTML][HTML] TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation

D Chatterjea, L Paredes, T Martinov, E Balsells… - …, 2013 - ncbi.nlm.nih.gov
… male ND4 Swiss mice are mediated by the degranulation of tissue-resident mast cells 2 . The
… caused by c48/80 that would have consequently affected mast cell-mediated hyperalgesia, …

Role of Toll-like receptor 4 signaling in mast cell-mediated migraine pain pathway

R Ramachandran, Z Wang, C Saavedra… - Molecular …, 2019 - journals.sagepub.com
… the development of compound 48/80-induced light avoidance in male mice, we assessed …
in the compound 48/80-induced light aversion. Administration of 48/80 in Myd88 −/− mice

The antinociception of oxytocin on colonic hypersensitivity in rats was mediated by inhibition of mast cell degranulation via Ca2+-NOS pathway

L Gong, J Li, Y Tang, T Han, C Wei, X Yu, J Li… - Scientific Reports, 2016 - nature.com
… exerted the inhibition of mast cell degranulation by Ca 2+ -NOS pathway in mast cells. …
mast cell degranulation in rats and the inhibition of OT on mast cell degranulation was mediated

[PDF][PDF] A mast-cell-specific receptor mediates neurogenic inflammation and pain

DP Green, N Limjunyawong, N Gour, P Pundir, X Dong - Neuron, 2019 - cell.com
… Recruitment in a Postoperative Model of Inflammation and Pain To ensure that the reductions
in inflammatory pain were not due to loss of mast cells in Mrgprb2 À/À mice, we used the …

P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice

K Yoshida, S Tanihara, Y Miyashita, K Obayashi… - Scientific Reports, 2022 - nature.com
… of the CP48/80-mediated degranulation reaction by ATP was mediated by the P2X4R. First,
… /80-mediated degranulation was absent in PMCs from P2rx4 −/− mice. PMCs prepared from …

[PDF][PDF] TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation [version 2; referees: 3 approved]

D Chatterjea, L Paredes, T Martinov, E Balsells, J Allen… - 2013 - Citeseer
… male ND4 Swiss mice are mediated by the degranulation of tissueresident mast cells2. The
… caused by c48/80 that would have consequently affected mast cell-mediated hyperalgesia, …

The mast cell stimulator Compound 48/80 causes urothelium-dependent increases in murine urinary bladder contractility

BM Jones, GC Mingin… - American Journal of …, 2023 - journals.physiology.org
… released after mast cell degranulation in C57Bl/6J mice. … if compound 48/80 induced
contractions were mediated by … is involved in compound 48/80-induced 356 contractions, …