… For other forms of muscular dystrophy like the limb girdle dystrophies, glucocorticoids are …
supporting multiple mechanisms of glucocorticoid action in dystrophic muscle including their …

… The exact mechanism by which steroids slow the dystrophic … Many clinicians use timed
and graded functional tests as a … Glucocorticoid receptor polymorphism may be implicated in …

… Inhibition of p70S6K, a target of mTOR that plays a key role in the protein synthesis
machinery, is thought to be one of the major mechanisms by which GCs cause muscle atrophy. …

… Corticosteroid therapy has been shown by a number of … understanding of the mechanism
of action of steroids, it might … after several decades of clinical use of steroids? One important …

… use, such as muscular dystrophy. On the other hand, less potent nonfluorinated varieties of
glucocorticoids … have suggested similar efficacy to that of prednisone (albeit at a higher dose), …

… weakness and degeneration_ This review, therefore, examines the available studies and
addresses various possible mechanisms involved m the efficacy of prednisone therapy and …

… mechanisms of glucocorticoid-induced muscle atrophy in … glucocorticoid-induced
hypogonadism and the possible relationship to the muscle atrophy in patients receiving …

… Although mechanisms governing GC-mediated muscle atrophy have been extensively
studied (1, 2), the molecular basis for their ergogenic effects remains poorly understood. …

… of the primary and secondary pathogenetic mechanisms. Guidelines for the multidisciplinary
care for Duchenne muscular dystrophy that address obtaining a genetic diagnosis and …

… The previous version of this review examined RCT evidence that showed corticosteroid
therapy in DMD improved muscle strength and function in the short term (six months), and …