… nanoparticles was investigated by analyzing the changes in metabolite profiles both in mouse
fibroblast (L929) cells … GC/TOFMS)-based metabolomic strategy. With multivariate statistics …

… Titanium dioxide nanoparticles (nano-TiO 2 ) have been widely … the disorder of carbohydrate
metabolism induced by nano-… 6 clearly revealed that the abnormal amino acid metabolism …

… cell function in human dermal fibroblasts and decreased cell area, cell proliferation, cell
mobility, and the ability of cells to … (A) Control group shows normal hepatic architecture and …

… concentration of titanium dioxide nanoparticles (nano-TiO 2 ) … -standing approach used for
metabolite profiling, offering a … , metabolic responses to nano-TiO 2 were studied in mouse …

… the proliferation of gingival fibroblasts (possibly for repair … highest cytotoxicity against a
mouse osteoblastic cell line MC3T3-… SE, as well as lignin–carbohydrate complex, shows potent …

… in untargeted metabolomics which make global metabolic profile … revealed the underline
mechanisms of toxicity induced by … of titanium dioxide nanoparticles-induced liver injury in mice: …

… The metabolic profiles of the two groups were further differentiated by an OPLS-DA …
Deregulations of carbohydrate metabolism, fatty acid metabolism, and … cytotoxicity might be …

… induced decreased levels of intestinal glucose absorption and increased levels of hepatic
glucose metabolism, … This study revealed for the first time the health risk of oral intake of TiO 2 -…

… LC-MS) based metabolomics was used to reveal significantly … , which defines the metabolic
profile closely linked to a … exposure caused significant reduction of inosine in the mouse lung …

… The gene expression profiles in this study revealed that the TiO 2 NPs treatment … to
metabolism (Table 5). These pathways are involved in lipid metabolism and glucose metabolism. …