Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2017 - pubs.rsc.org
… The microfluidic platforms presented in this section demonstrate the capability to perform
chemical biology and genetic screens based on electrophysiological phenotyping, including …
chemical biology and genetic screens based on electrophysiological phenotyping, including …
Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping
S Mondal, A Ben-Yakar - Organ-on-a-chip, 2020 - Elsevier
… , the only large-scale microfluidics platform to date that can immobilize 4000 … microfluidic
platform that enables high-throughput and high-content imaging of several thousands of C…
platform that enables high-throughput and high-content imaging of several thousands of C…
An automated microfluidic platform for calcium imaging of chemosensory neurons in Caenorhabditis elegans
… We utilized the microfluidic platform to characterize and quantify the effect of aging to the
excitability of the ASH chemosensory neuron. We monitored the activity of ASH in response to a …
excitability of the ASH chemosensory neuron. We monitored the activity of ASH in response to a …
Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies
J Krajniak, H Lu - Lab on a Chip, 2010 - pubs.rsc.org
… , in combination with a microfluidic platform. The system allows us to culture, individually track
… repeatedly image C. elegans at high resolution directly inside a microfluidic device while …
… repeatedly image C. elegans at high resolution directly inside a microfluidic device while …
A microfluidic platform for lifelong high-resolution and high throughput imaging of subtle aging phenotypes in C. elegans
S Saberi-Bosari, J Huayta, A San-Miguel - Lab on a Chip, 2018 - pubs.rsc.org
… high-resolution aging studies on C. elegans with a large sample size poses various
technical difficulties. In this study, we designed and fabricated a microfluidic platform capable of …
technical difficulties. In this study, we designed and fabricated a microfluidic platform capable of …
Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis
L Dong, R Jankele, M Cornaglia, T Lehnert… - … Science, 2018 - Wiley Online Library
… This work reports a fully integrated microfluidic approach for studies of C. elegans early
embryogenesis, including the possibility of testing small molecule inhibitors with increased …
embryogenesis, including the possibility of testing small molecule inhibitors with increased …
Microfluidic approaches for Caenorhabditis elegans research
E Levine, KS Lee - Animal cells and systems, 2020 - Taylor & Francis
… Caenorhabditis elegans is a small soil nematode with many advantages as a research
model organism. It is easy to cultivate with a reproduction cycle of a few days, and its short …
model organism. It is easy to cultivate with a reproduction cycle of a few days, and its short …
[HTML][HTML] Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform
… multiplexed microfluidic platform for automated phenotyping of C. elegans embryos during
… Caenorhabditis elegans embryos were obtained through a classical bleaching procedure in …
… Caenorhabditis elegans embryos were obtained through a classical bleaching procedure in …
Advances in C. áelegans behavior research with microfluidic devices and its future prospects in the evaluation of exogenous pollutants
… The nematode Caenorhabditis elegans (C.áelegans) is characterized by small size, a …
microfluidic platform to conduct rapid high-content phenotypic analyses of multiple individuals of C.…
microfluidic platform to conduct rapid high-content phenotypic analyses of multiple individuals of C.…
An in vivo microfluidic study of bacterial transit in C. elegans nematodes
… (ad465) mutant C. elegans strains in both trapped and free-swimming conditions. In
order to further demonstrate the versatility of our microfluidic platform, we also studied drug-induced …
order to further demonstrate the versatility of our microfluidic platform, we also studied drug-induced …