An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging

M Cornaglia, L Mouchiroud, A Marette, S Narasimhan… - Scientific reports, 2015 - nature.com
… of Caenorhabditis elegans, one of the most employed model organisms in biomedical research.
We developed a microfluidic platform … We successfully employ our platform to investigate …

A microfluidic device for efficient chemical testing using Caenorhabditis elegans

P Song, W Zhang, A Sobolevski, K Bernard… - Biomedical …, 2015 - Springer
… The nematode worm Caenorhabditis elegans has been employed as a popular model … In
this paper, we present a microfluidic device for facilitating chemical testing using C. elegans. …

Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

S Mondal, E Hegarty, C Martin, SK Gökce… - Nature …, 2016 - nature.com
elegans, we developed an automated microfluidic platform. This platform can image 15 z-stacks
of ∼4,000 C… Integrated with optomechanical systems, microfluidic platforms enable …

Studying Parkinson's disease using Caenorhabditis elegans models in microfluidic devices

K Youssef, A Tandon, P Rezai - Integrative Biology, 2019 - academic.oup.com
… In this review, we focus on C. elegans PD models and the recent advancements in microfluidic
platforms used for manipulation, handling and neurobehavioral screening of these models…

Digital Microfluidics Supported Microproteomics for Quantitative Proteome Analysis of Single Caenorhabditis elegans Nematodes

MK Steinbach, J Leipert, C Blurton… - Journal of Proteome …, 2022 - ACS Publications
… Here, we demonstrate a highly sensitive digital microfluidics (… changes in single Caenorhabditis
elegans treated with a … technology for low-input proteomics studies. LC-MS data have …

Microfluidic-based electrotaxis for on-demand quantitative analysis of Caenorhabditis elegans' locomotion

J Tong, P Rezai, S Salam, PR Selvaganapathy… - JoVE (Journal of …, 2013 - jove.com
… The nematode Caenorhabditis elegans is a versatile model organism for biomedical research
because of its conservation of disease-related genes and pathways as well as its ease of …

NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans

M Rahman, H Edwards, N Birze, R Gabrilska… - Scientific reports, 2020 - nature.com
… this study, we report a microfluidic device for the whole-life culture of the nematode
Caenorhabditis elegans … We also show that the culture of animals in pillar-less microfluidic

Profile analysis of C. elegans rheotaxis behavior using a microfluidic device

A Ge, X Wang, M Ge, L Hu, X Feng, W Du, BF Liu - Lab on a Chip, 2019 - pubs.rsc.org
… In this work, we presented a rapid and robust microfluidic approach to quantitatively analyze
… , our microfluidic method provides a useful platform to study the rheotaxis behaviors in C. …

Hydrogel-droplet microfluidic platform for high-resolution imaging and sorting of early larval Caenorhabditis elegans

G Aubry, M Zhan, H Lu - Lab on a Chip, 2015 - pubs.rsc.org
… 6b–c). We also compared the image quality obtained with the microfluidic platform to the one
using conventional methods, as the use of Pluronic, the presence of silicone oil film and the …

The Egg-Counter: A novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying

SA Banse, CM Jarrett, KJ Robinson, BW Blue… - Lab on a Chip, 2024 - pubs.rsc.org
… Here, we present a novel microfluidic research platform for studying Caenorhabditis elegans
We provide a microfluidic device design, a temperature control system, image acquisition …