An automated microfluidic system for screening Caenorhabditis elegans behaviors using electrotaxis

D Liu, B Gupta, PR Selvaganapathy - Biomicrofluidics, 2016 - pubs.aip.org
… The results show the potential of our new microfluidic platform in rapid screening of C.
elegans movement behavior under electric fields as well as future screenings of mutants and …

[HTML][HTML] A multi-trap microfluidic chip enabling longitudinal studies of nerve regeneration in Caenorhabditis elegans

SK Gokce, EM Hegarty, S Mondal, P Zhao… - Scientific reports, 2017 - nature.com
microfluidic platformsstudies 23, 24 , phenotyping 25, 26 , behavioral studies 27,28,29
, electro-physiology 30 , and laser surgery 4, 13, 26, 31 . A few different microfluidic platforms

Microfluidic tools for developmental studies of small model organisms–nematodes, fruit flies, and zebrafish

H Hwang, H Lu - Biotechnology journal, 2013 - Wiley Online Library
Caenorhabditis elegans has also proven to be a powerful tool for the pharmaceutical industry
and as for fundamental studies of … Microfluidic platforms could dramatically enhance our …

[HTML][HTML] Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

HB Atakan, R Xiang, M Cornaglia, L Mouchiroud… - Scientific reports, 2019 - nature.com
… 80 hours of automated single worm culture studies. Our microfluidic platform is linked with an
… We validated our platform with a dose-response study of the anthelmintic drug tetramisole …

Soil-on-a-Chip: microfluidic platforms for environmental organismal studies

CE Stanley, G Grossmann, XC i Solvas, AJ deMello - Lab on a Chip, 2016 - pubs.rsc.org
Caenorhabditis elegans is a model organism commonly used in biological (particularly in
the fields of evolutionary biology and aging research 51 ) and toxicological screens. The …

Microfluidic devices for imaging and manipulation of C. elegans

AS Clark, J Huayta, KS Arulalan… - … Studies of Cells and Small …, 2021 - Elsevier
… Although not common, other methods are used to immobilize C. elegans within microfluidic
platforms. One early immobilization technique takes advantage of PDMS diffusivity to …

A microfluidic phenotype analysis system reveals function of sensory and dopaminergic neuron signaling in C. elegans electrotactic swimming behavior

S Salam, A Ansari, S Amon, P Rezai… - Worm, 2013 - Taylor & Francis
… We conclude that our microfluidics setup can be used to identify and study factors affecting
DA … Thus, the microfluidic platform can be used as an effective and non-invasive tool to detect …

Development of an integrated microfluidic device for evaluating of in vivo chemo-sensing of intact Caenorhabditis elegans

J Wang, Z Li, Z Xu, L Hu, X Feng, M Chen, W Du… - Sensors and Actuators B …, 2013 - Elsevier
… subject is small model organism Caenorhabditis elegans. In this paper, we demonstrate
a powerful microfluidic device that allowed investigating in vivo chemo-sensing of intact C. …

Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans

N Chronis, M Zimmer, CI Bargmann - Nature methods, 2007 - nature.com
… In this work we extend the applications of microfluidics to in vivo C. elegans imaging. We …
We envision microfluidics as a general manipulation platform for neuronal and behavioral …

Microfluidic chip-based C. elegans microinjection system for investigating cell–cell communication in vivo

X Zhao, F Xu, L Tang, W Du, X Feng, BF Liu - Biosensors and Bioelectronics, 2013 - Elsevier
… We expect this novel microfluidic platform to be a useful tool for studying cell–cell … microfluidic
platform for investigating the propagation of ICW induced by chemical stimulation in live C. …