… But mainly due to the risks associated with permanent genetic alteration of cells, safety and
… In the last years, synthetic messenger RNA has emerged as powerful tool to deliver genetic …

… in development of vaccines inducing specific T-cell responses. … , such as those derived from
the TAT protein, or of various … The 5′ and 3′ ends of the ORF were modified by insertion of …

… Tat protein, which is essential for HIV-1 replication, has a … As expected, vRPS-CTP/p24
induced strong CTL responses in … B7.2 to the immune response to recombinant modified vaccinia …

… the induction of a vaccine specific systemic immune response, … Modification of CEA with
both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC …

… is appropriate target for DC vaccination using cell-penetrating … potent target cell type for
modulating the immune system … could modulated OVA-induced allergic T cell responses in vivo …

… inducing a robust CD8 (cytotoxic) T cell immune response. In … been assayed in order to
activate these RNA-pulsed cells [21]. … around 2–4 × 10 8 DC in our hands when using two mice. …

… , we selected 2 tumor cells, MC32-S2-2 and MC32-S4-2, which have the ability to form tumors
in CEA DNA vaccine-… Antitumor activity and immune responses induced by a recombinant …

… effect of Tat-Hsp-27 in preventing hypoxia-induced cellular … impact of Tat-Hsp27 mediated
blockade on both apoptotic … Our result confirms other studies that PTD is able to deliver …

Bundred NJ, Campbell ID, Davidson N, et al. Effective inhibition of aromatase inhibitor-associated
bone loss by zoledronic acid in postmenopausal women with early breast cancer …

… enhance the efficacy of anti-tumor vaccinations by neutralizing … is to in vivo stimulate the
adaptive immune system to achieve tumor … for inducing a specific T response against CEA [106]. …