… genetically-modified mouse, transgenic animals have been … transgenic animals have been
used in functional genomics … Recent advances in genome modification techniques such zinc …

… applied to facilitate the generation of gene-modified animals that express specific and
desired traits, … Sheep were among the first domestic animals that are subjected to embryo-splitting …

… genome editing to these areas. It is obvious that the effectiveness and specificity of genome
… ethical concerns of using genetic modified tissues, organs and animals remain a focus of …

… genome sequencing projects for various farm animal species are completed, it has become
feasible to perform precise genetic modifications … genetic modification of farm animals will be …

… In summary, the ongoing improvements in genome modification tools with avian embryo
manipulation and PGC culture continues to refine the production of GE avian species with …

… editing to generate genetically modified animals, as well as in … true pluripotent ESCs in
domesticated animals such as pigs … genomic hybridization to carefully monitor the integrity of the …

… extensively to create inheritable genetic modifications in a multitude of non-human animals
from insects to mammals. The availability of genome edited animals has profound impacts on …

… in disease pathways provide model animals to improve our … The completed sequencing
of the swine genome will … for gene modification with the completion of the swine genome will …

… and animal model in biomedical studies. Efficient and precise modification of pig genome
by … introduce predetermined modifications, including knockouts and knockins, into the pig …

… Indeed, the health of domesticated animal populations is closely … of genomic regions implicated
in traits of interest in … , but this default may be modified by the command-line parameter -…