Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels

PEM Martin, G Blundell, S Ahmad… - Journal of cell …, 2001 - journals.biologists.com
… In the present work we show that trafficking of fluorescently tagged Cx43 and 32 and their
assembly into gap junctions were disrupted by BFA treatment or by lowering the ambient …

Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways

PEM Martin, RJ Errington, WH Evans - Cell communication & …, 2001 - Taylor & Francis
43 thus appear to be transported and assembled into gap junctions via the classical secretory
pathway… Rapid appearance of connexin 26-positive gap-junctions in centrilobular …

[HTML][HTML] Cytomembrane trafficking pathways of Connexin 26, 30, and 43

YJ Zong, XZ Liu, L Tu, Y Sun - International Journal of Molecular Sciences, 2023 - mdpi.com
gap junction formation, ultimately leading to connexin … for connexin 43, connexins 30
and 26, mutations affecting … and Cx30 assemble into two types of gap junctions that form a …

[HTML][HTML] Intracellular trafficking pathways of Cx43 gap junction channels

I Epifantseva, RM Shaw - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
… Of all 20 murine and 21 human connexins, Connexin 43 (Cx43… , assembly on the plasma
membrane, retrograde trafficking, … trafficking and localization of full length Cx43 gap junction

[HTML][HTML] Regulation of connexin biosynthesis, assembly, gap junction formation, and removal

D Segretain, MM Falk - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
… ) trafficking along microtubules, (6) insertion of connexons into … , no gap junction channel
assembly or gap junction plaque … to interfere with the secretory pathway, such as brefeldin A (…

Cytomembrane Trafficking Pathways of Connexin 26, 30 and 43: Recent Updates

YJ Zong, X Liu, L Tu, Y Sun - 2023 - preprints.org
gap junction formation, ultimately leading to connexin … for connexin 43, connexins 30
and 26, mutations affecting … and Cx30 assemble into two types of gap junctions that form a …

Incorporation of connexins into plasma membranes and gap junctions

PEM Martin, WH Evans - Cardiovascular research, 2004 - academic.oup.com
assembly of connexins into gap junctions and discusses those protein domains that regulate
trafficking routes. … that Cx32 and 43 are trafficked via the secretory pathway whereas Cx26 …

Actin-independent trafficking of cochlear connexin 26 to non-lipid raft gap junction plaques

J Defourny, N Thelen, M Thiry - Hearing Research, 2019 - Elsevier
… We observed that Cx26 assembly occurs in non-lipid raft … that cochlear Cx26 gap junction
assembly requires microtubules … into Cx26 trafficking pathway and gap junction assembly in …

Pathways for degradation of connexins and gap junctions

VM Berthoud, PJ Minogue, JG Laing… - Cardiovascular …, 2004 - academic.oup.com
… ; (2) connexins (as monomers or oligomers) may traffic directly … ; (3) connexins within gap
junction plaques are degraded by … (or assemble) gap junction channels into functional plaques …

[HTML][HTML] Connexins: a myriad of functions extending beyond assembly of gap junction channels

HA Dbouk, RM Mroue, ME El-Sabban… - Cell Communication and …, 2009 - Springer
… the connexins with molecular weight 26 kDa, 32 kDa and 43 … degradation pathway may
regulate connexin stability and … in the organization and trafficking of gap junctions. In a study …