Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer

A Honig, C Weidler, S Häusler… - Anticancer …, 2010 - ar.iiarjournals.org
… published, which investigated the role of BMI-1 in a variety of tumors (11-14). … the BMI-1
expression in a subset of human specimens of breast ovarian, endometrial and cervical cancers

Relationship between polycomb‐group protein BMI1 and phosphatases regulating AKT phosphorylation level in endometrial cancer

A Zaczek, P Jóźwiak, P Ciesielski… - Journal of Cellular …, 2020 - Wiley Online Library
… types of human cancers, including gastric, ovarian, breast, … of BMI-1 in samples of more
advanced endometrial carcinomas (… Despite the fact that overexpression of BMI-1 is involved in …

Clinicopathological and prognostic significance of Bmi1 expression in human cervical cancer

L Min, S DONG‐XIANG… - Acta obstetricia et …, 2011 - Wiley Online Library
… belonging to the polycomb group family of proteins, which are … , endometrial and cervical
cancer (11). Chen et al. showed … found that the overexpression of Bmi-1 protein had important …

Immunohistochemical expression and prognostic relevance of Bmi-1, a stem cell factor, in epithelial ovarian cancer

HA El-Hadaad - Annals of diagnostic pathology, 2014 - Elsevier
… of Bmi-1 protein in epithelial ovarian cancer tissue specimens and … Overexpression of Bmi-1
immortalizes human mammaryOverexpression of polycomb protein Bmi-1 has been linked …

[HTML][HTML] BMI1, a promising therapeutic target for human cancer

MC Wang, CL Li, J Cui, M Jiao, T Wu… - Oncology …, 2015 - spandidos-publications.com
BMI1 oncogene is a member of the polycomb‑group gene … (HCC) and endometrial carcinoma
(8–16). In addition, … The overexpression of BMI-1 in gastric and breast cancer has been …

Prognostic role of high Bmi-1 expression in Asian and Caucasian patients with solid tumors: a meta-analysis

Y Shao, Y Geng, W Gu, Z Ning, J Jiang, H Pei - Biomedicine & …, 2014 - Elsevier
Bmi-1 is one of the core members of the polycomb … data, one detected Bmi-1 not in tissue
sample, three investigated the … evidence indicating that overexpression of Bmi-1 alone may not …

The role of BMI1 in endometrial cancer and other cancers

Y Zhao, W Yang, K Zheng, J Chen, X Jin - Gene, 2023 - Elsevier
… is one of the core members of the polycomb group (PcG) family, which … and overexpressed
in various tumors, including cervical cancer, … localization of the human proto-oncogene BMI-1

[HTML][HTML] The crucial roles of Bmi-1 in cancer: implications in pathogenesis, metastasis, drug resistance, and targeted therapies

J Xu, L Li, P Shi, H Cui, L Yang - International Journal of Molecular …, 2022 - mdpi.com
Bmi-1 protein belongs to the polycomb family of … Similarly, Bmi-1 overexpression promoted
migration and proliferation of … of Bmi-1 reduces the migration and invasion of endometrial

Inhibition of BMI1, a therapeutic approach in endometrial cancer

M Buechel, A Dey, SKD Dwivedi, A Crim, K Ding… - Molecular cancer …, 2018 - AACR
polycomb ring finger protein BMI1, also known as a stem cell factor, is significantly overexpressed
in endometrial cancer cell lines, endometrial … to breast, ovarian, and cervical cancer, …

[HTML][HTML] Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and …

MC Wang, M Jiao, T Wu, L Jing, J Cui, H Guo, T Tian… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Overexpression of BMI-1 could stimulate malignant … was localized in the nucleus and detected
in 35 of the 83 tumor samples (… cells, such as endometrial cancer, oral cancer, lung cancer