… PDE4A, 4B, 4C, and 4D mRNA subtypes are present in human … genetic variations and β
agonists among asthma patients by … , showed significant associations with responsiveness of β2 …

… selective PDE inhibitors in the treatment of COPD and asthma. … relies mainly on the use of
bronchodilators (β 2 -adrenoceptor (… the role of PDE3 in an acute house dust mite-driven (HDM-…

… of genetic polymorphisms have been associated … of bronchodilators to control acute symptoms
is a danger sign of an impending crisis. Treatment includes oxygen, inhaled short-acting 2-…

… 13 gene polymorphisms and their association with asthma and … an estimated 4.3% children
suffer from asthma in Pakistan. … bronchodilators and increased use of systemic steroids [34]. …

… Involvement of LTs C 4 /D 4 /E 4 has been demonstrated in … symptoms, and reduction in
short-acting β-agonist (SABA) use in … and the efficacy of bronchodilator is controversial; however, …

… of genetic polymorphisms and adipokines effects in children … pathway, which further
responds by releasing anorexigenic … were not associated with asthma in children (Citation21). …

… 17q21 strongly associated with childhood-onset asthma. Variation … to repetitive or continuous
administration of short-acting … evaluating levalbuterol and albuterol for acute asthma in all …

… cell influx vs placebo or a short-acting β 2 -agonist. … LABAs act primarily as bronchodilators,
but also inhibit mast cell … PDE-4D messenger RNA expression and the down-modulation of …

… beta-2 adrenergic agonists are administered for the acute relief … beta-2 agonists for asthmatic
patients that are poorly controlled … of more potent bronchodilators such as short-acting beta-…

… ) gene has been thought to have an important role in the differential response to β 2 -agonist
therapy for asthma… However, previous studies have shown little evidence for an association …