[PDF][PDF] Hospitals Birmingham, Birmingham, B15 2TH, UK. Correspondence: Robert A Stockley. Email: Rob. stockley@ uhb. nhs. uk or ra stockley@ bham. ac. uk

AM Wood, SL Tan - researchgate.net
… the administration of short acting bronchodilators, together … inflammatory treatment in children
with asthma: rationale and … : Association of phosphodiesterase 4D gene polymorphisms

RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells

BE Himes, X Jiang, P Wagner, R Hu, Q Wang… - PloS one, 2014 - journals.plos.org
response and short-acting bronchodilator response). … [Figure 4D], again supporting a role
for CRISPLD2 in modulating IL1β … asthmatics from the following drug clinical trials: Childhood

Chronic obstructive pulmonary disease: role of matrix metalloproteases and future challenges of drug therapy

PK Srivastava, SG Dastidar, A Ray - Expert opinion on …, 2007 - Taylor & Francis
… flow and associated abnormal inflammatory responses of the … mediator of pathogenesis of
acute and chronic lung injuries. … Short-acting β 2 agonists such as albuterol (nasal formulation…

Pharmacogenetics, pharmacogenomics and gene therapy

IP Hall - Pharmacology and Therapeutics of Asthma and COPD, 2004 - Springer
… a short-acting ,82-agonist in asthma) it may be valuable where … For example, the human
phosphodiesterase 4D gene cov- … of the ,8radrenoceptor and response to albuterol in children

Rhinovirus C15 attenuates relaxation and cAMP production in human airways and smooth muscle

EB Gebski, V Parikh, H Lam, N Kim… - American journal of …, 2023 - atsjournals.org
… Additionally, we show that Iso (a short-acting β 2 AR agonist), … study of pediatric patients
with asthma found that the children … Here we sought to examine responses to bronchodilators

Airway smooth muscle in the pathophysiology and treatment of asthma

DC Doeing, J Solway - Journal of applied physiology, 2013 - journals.physiology.org
associated with the clinical syndrome of asthma. In … hyperinflation that attends acute asthma
attacks may be less … /Arg16 genotype exhibit reduced bronchodilator responses to inhaled β-…

Pharmacology of the Airways

PJ Wojciechowski, WE Hurford - Principles and Practice of Anesthesia for …, 2011 - Springer
… beta-2 adrenergic agonists are administered for the acute relief of … of more potent
bronchodilators such as short-acting beta-… Patients that have allergen-induced asthma or patients

YKL-40 and genetic status of CHI3L1 in a large group of asthmatics

JW Hansen, SF Thomsen, C Porsbjerg… - European clinical …, 2015 - Taylor & Francis
… We studied the relationship between clinical asthmaShort-acting inhaled bronchodilators
should be discontinued for … be a biomarker of both acute and chronic inflammatory activity. We …

Peripheral blood gene expression predicts clinical benefit from anti–IL-13 in asthma

DF Choy, G Jia, AR Abbas, KB Morshead… - Journal of Allergy and …, 2016 - jacionline.org
… from type 2 pathway–directed therapies in pediatric asthma is … novel associations in vivo
with respect to asthmatic type 2 … obstruction with a short-acting bronchodilator or methacholine …

Leukotrienes

M Peters-Golden… - New England Journal of …, 2007 - Mass Medical Soc
… to type 1 cysteinyl leukotriene receptor (CysLT 1 ) in asthma … in myriad cellular and tissue
responses. The sites of action of … membrane is associated with a maximal synthesis of LTB 4 . …