Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short‐Acting Bronchodilators in Paediatric Asthma Patients
M Labuda, S Laberge, J Briere, D Bérubé… - Mediators of …, 2011 - Wiley Online Library
… The aim of this study was to test whether genetic variants in PDE4D gene, a … genetic variants
in PDE4D gene as potential predictive factor of the response to a single dose of short-acting …
in PDE4D gene as potential predictive factor of the response to a single dose of short-acting …
RGS5 gene and therapeutic response to short acting bronchodilators in paediatric asthma patients
M Labuda, S Laberge, J Brière, D Bérubé… - Pediatric …, 2013 - Wiley Online Library
… variant in phosphodiesterase 4D (PDE4D)13 gene, an … the relationship between RGS5 gene
polymorphisms and … explore the association of RGS5 genetic variations and response to β2-…
polymorphisms and … explore the association of RGS5 genetic variations and response to β2-…
Effects of PDE4 gene polymorphisms on efficacy and adverse drug events of ritodrine therapy in preterm labor patients: a prospective observational study
J Yee, HS Hwang, JE Chung, JY Park, KE Lee… - European Journal of …, 2019 - Springer
… PDE families that display high affinity to cAMP, of which the PDE4A, 4B, 4C, and 4D mRNA
… ], alters ritodrine efficacy due to its association with physiological processes of the β2 agonist…
… ], alters ritodrine efficacy due to its association with physiological processes of the β2 agonist…
Pharmacogenetics of respiratory disease
IP Hall, SB Liggett - Pharmacogenetics, 2016 - api.taylorfrancis.com
… the clinical response to repetitive administration of short-acting … The phosphodiesterase
(PDE) 4D subfamily is thought to be … no specific gene polymorphisms have been associated with …
(PDE) 4D subfamily is thought to be … no specific gene polymorphisms have been associated with …
[PDF][PDF] Evaluation of patients with nasal polyps about the possible association of desmosomal junctions, RORA and PDE4D gene
T Apuhan, S Gepdiremen, AO Arslan… - European review for …, 2013 - europeanreview.org
… This is likely linked to the mucosal inflammatory response. … 32 allel G and 60.87 for allel A
RORA polymorphism of the … also activates and phosphorylates phosphodiesterase 4 (PDE4) …
RORA polymorphism of the … also activates and phosphorylates phosphodiesterase 4 (PDE4) …
Pharmacogenetics of chronic obstructive pulmonary disease
N Hizawa - Pharmacogenomics, 2013 - Taylor & Francis
… before and after administration of a short-acting β2-agonist. … ADRB2 polymorphisms on
treatment response to short-acting … examined the association of the ADRB2 polymorphisms and …
treatment response to short-acting … examined the association of the ADRB2 polymorphisms and …
Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis
… treatment of systemic sclerosis (SSc)-associated ILD and other chronic fibrosing ILDs
with a … polymorphisms are correlated with ischaemic stroke [30] and response to short-acting …
with a … polymorphisms are correlated with ischaemic stroke [30] and response to short-acting …
Chronic obstructive pulmonary disease: towards pharmacogenetics
AM Wood, SL Tan, RA Stockley - Genome Medicine, 2009 - Springer
… less than 0.7 after the administration of short acting bronchodilators, together with an impaired
… given polymorphism. Using these stricter standards for genetic association, the genes or …
… given polymorphism. Using these stricter standards for genetic association, the genes or …
Pharmacogenomics of Allergy and Asthma
… -1 Val762Ala polymorphism may be directly associated with … The predicting model to
short-acting bronchodilators was … the role of HNMT gene polymorphisms in the pathogenesis of …
short-acting bronchodilators was … the role of HNMT gene polymorphisms in the pathogenesis of …
Effects of Phosphodiesterase Variants on Angiogenic Functions of Vascular Endothelial Cells
K Monteith - 2021 - search.proquest.com
… Genetic variants of PDE4D have been associated with the response to short-acting … siRNA
designed to silence all known cyclic nucleotide phosphodiesterase 4D (PDE4D) transcripts, or …
designed to silence all known cyclic nucleotide phosphodiesterase 4D (PDE4D) transcripts, or …