… Pathophysiological implications This review has summarized the photodegradation of melanin
… With lower doses, DHI units in eumelanin are oxidized to indolequinone units, a process …

… Finally, what would be the pathophysiological implications of the present finding that VL
accelerates the UVA-induced photodegradation of eumelanin and pheomelanin? The direct …

… into l-DOPA and other oxidation products, which are reactive among themselves, favoring
self-polymerization and production of two main types of melanin: eumelanin and pheomelanin. …

… However, it should be noted that pheomelanin, unlike eumelanin, undergoes photodegradation
under the influence of UV radiation, resulting in the production of hydrogen peroxide, …

… properties of photodegraded melanin may result from the depletion of its catechol units. This
… Photodegradation of eumelanin and pheomelanin and its pathophysiological implications. …

… and indole units, with cysteine in its pheomelanin core and eumelanin on its surface [76]. …
Nigrasomes should contain pheomelanin in the core and eumelanin on the surface [77]. …

… Pheomelanin also undergoes photodegradation during PPD … , pheomelanin may not
contribute much to PPD due to its … might also play a role in its physiopathology and that long-term …

… We also analyzed possible phototoxic effects of photodegraded hair melanosomes of …
Therefore, the conversion of pheomelanin subunits accompanying photodegradation would …

… Although eumelanins and pheomelanins have the primary biogenetic precursor tyrosine
in common, they differ significantly in their chemical composition and physical properties. …

… effects of UVR on human skin, the properties of melanin, the regulation of pigmentation and
… In contrast to eumelanin, pheomelanin is especially prone to photodegradation (78,79) and …