… by the selective destruction of pancreatic β cells, followed by … a streptozotocin (STZ)-induced
type I diabetic mouse model. … -soluble derivative of propolis does not elicit toxic effects. …

… mg/kg of streptozotocin (STZ) (Sigma chemical co. PO Box. 14508, st. … (200 mg/kg) prevented
β cells destruction by inhibiting IL-1β … toxicity in pancreatic islet beta cell in diabetes. J. Biol. …

… -3, IL-1β, and TBARSs in the pancreatic tissues of STZ-diabetic rats. … regenerating pancreatic
β-cells and ameliorating pancreatic … of β-cells and enhancing islet revascularization in STZ-…

… pancreatic β cells. c Diabetic control rat (DC) showing a weak insulin immunoreactivity in the
pancreatic β cells … β cells against STZ toxicity, as indicated by reducing the hyperglycemia. …

… The study compared 60 streptozotocin (STZ)-induced diabetic rats, … insulin in propolis-treated
diabetic rats could be the β cells of … treatment of STZ-induced diabetic rats with propolis and …

… hyperglycaemia caused by streptozotocin. Standard protocols … the dose of propolis extract
at 250mg/Kg and serve as (STZ + … Two tales of antioxidant enzymes on β cells and diabetes. …

… Strptozocin (STZ) is known to have toxic effects on pancreatic β-cells and may be used as a
… of STZ as a diabetic inducer in experimental animals. Intraperitoneal injection of STZ leads …

… activity of chrysin against streptozotocin (STZ)-induced … in GLUT2 levels in pancreatic β
cells in diabetic animals ( 9 ). … aerial parts as well as honey and propolis ( 14 ). It has been …

… Most of the authors used streptozotocin (STZ) as a diabetes … (200 mg/kg) showed a preventive
effect on pancreatic β-cells … laboratory, propolis did not seem to counteract STZ effects, …

… a single dose of 130mg/kg body weight of streptozotocin (STZ). … of propolis) is not toxic,
according to the OECD 423 acute … on pancreatic 𝛽-cells by stimulating the few surviving 𝛽-cells to …