Protein kinase CK2, an important regulator of the inflammatory response?

NN Singh, DP Ramji - Journal of molecular medicine, 2008 - Springer
… This review will give an overview of CK2 and its regulation and describe the evidence … It is
now described as protein kinase CK2 or commonly CK2. Other “casein” kinases, such as CK1 …

[HTML][HTML] Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation

S Koch, CT Capaldo, RS Hilgarth, B Fournier… - Mucosal …, 2013 - Elsevier
Protein kinase CK2 is critically involved in many homeostatic signaling events, and its
expression and activity is increased in virtually all cancers, where it is thought to confer growth …

Protein kinase CK2 in health and disease: Cellular functions of protein kinase CK2: a dynamic affair

O Filhol, C Cochet - Cellular and Molecular Life Sciences, 2009 - Springer
Protein kinase CK2 targets a vast array of substrates located in a number of cellular compart…
a signaling protein, CK2 could be targeted to different cellular compartments in response to …

[HTML][HTML] The immune regulatory role of protein kinase CK2 and its implications for treatment of cancer

H Hong, EN Benveniste - Biomedicines, 2021 - mdpi.com
… There is increasing interest in using CK2 inhibitors for the treatment of various cancers. In …
CK2 regulates the function of immune cells that are important for mounting immune responses

Protein kinase CK2 in human diseases

B Guerra, OG Issinger - Current medicinal chemistry, 2008 - ingentaconnect.com
kinases, such as the Cdk kinases. There are some peculiarities associated with protein kinase
CK2… A crosstalk between CK2 and the NF-kappaB-dependent inflammatory response has …

The role of protein kinase CK2 in intestinal epithelial cell inflammatory signaling

K Parhar, J Morse, B Salh - International journal of colorectal disease, 2007 - Springer
… adaptive immune response plays a critical role in the pathogenesis of inflammatory bowel …
this work reports on the role of protein kinase CK2 in the NF-κB activation response to IL-1β in …

[HTML][HTML] The role of protein kinase CK2 in development and disease progression: a critical review

D Halloran, V Pandit, A Nohe - Journal of Developmental Biology, 2022 - mdpi.com
… , and spermatogenesis is essential for the viability of almost all … adulthood, CK2 continues
to function as a key regulator of … , neuron differentiation, and the immune response. Due to its …

Protein kinase 2 (CK2): A potential regulator of immune cell development and function in cancer

K Husain, TT Williamson, N Nelson… - Immunological …, 2021 - Taylor & Francis
immune cells. However, very few research studies have focused on extrinsic role of CK2 in
regulating immune responses … Prior studies have even demonstrated that protein kinase CK2

[HTML][HTML] Protein kinase CK2: a potential therapeutic target for diverse human diseases

C Borgo, C D'Amore, S Sarno, M Salvi… - Signal transduction and …, 2021 - nature.com
CK2 (previously called casein kinase 2 or CK-II) is one of the first identified protein kinases.
It phosphorylates hundreds of physiological substrates, 2 and is one of the major contributors …

[图书][B] Protein kinase CK2

LA Pinna - 2012 - books.google.com
… paradox of CK2: many oncogenes encode protein kinases endowed with … CK2 from being
an oncogene, since no gain of function mutations have ever been reported, nonetheless CK2