Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells
MN Nikiforova, JR Stringer, R Blough, M Medvedovic… - Science, 2000 - science.org
… rearrangements are not found in breast cancers in humans (23). In light of our findings, it is
reasonable to postulate that RET/PTC1 rearrangements in human mammary cells … these cells. …
reasonable to postulate that RET/PTC1 rearrangements in human mammary cells … these cells. …
Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells
L Brianna Caddle, JL Grant, J Szatkiewicz… - Chromosome …, 2007 - Springer
… positioning and average proximity of the participating CTs in … radiation-induced translocations
in p53-deficient cells is, at … reflect how chromosomes have become rearranged during …
in p53-deficient cells is, at … reflect how chromosomes have become rearranged during …
Radiation‐induced chromosome aberrations: insights gained from biophysical modeling
L Hlatky, RK Sachs, M Vazquez, MN Cornforth - Bioessays, 2002 - Wiley Online Library
… 46) The need for close spatial proximity of loci in an aberrationforming interaction, … Proximity
of chromosomal loci that participate in radiation-induced rearrangements in human cells. …
of chromosomal loci that participate in radiation-induced rearrangements in human cells. …
[HTML][HTML] Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human …
… of chromosome rearrangements, we characterised the complexity of radiation-induced
chromosome … 5), we did find two interactions that involved chromosomes previously detected in …
chromosome … 5), we did find two interactions that involved chromosomes previously detected in …
[HTML][HTML] Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
C Lin, L Yang, B Tanasa, K Hutt, B Ju, KA Ohgi… - Cell, 2009 - cell.com
… may initially result from random chromosome rearrangement events, which are ultimately …
in LNCaP cells (Figures S6A and S6B). In contrast, the BCR and ABL1 gene loci did not …
in LNCaP cells (Figures S6A and S6B). In contrast, the BCR and ABL1 gene loci did not …
Ionizing radiation‐induced chromosomal rearrangements occur in transcriptionally active regions of the genome
HB Forrester, IR Radford - International journal of radiation biology, 2004 - Taylor & Francis
… genes: evidence for gene proximity in specific phases of the cell cycle and stages of … ,
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. …
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. …
Influence of nuclear structure on the formation of radiation-induced lethal lesions
DA Friedman, L Tait, ATM Vaughan - International Journal of …, 2016 - Taylor & Francis
… chromosome proximity is a key element in rearrangement … Cross-linked loci may be on the
same or different chromosomes. … Thus it is apparent that transcriptional programs are involved …
same or different chromosomes. … Thus it is apparent that transcriptional programs are involved …
Investigation of spatial organization of chromosome territories in chromosome exchange aberrations after ionizing radiation exposure
… of chromosome domains in ionizing-radiation-induced … of chromosome proximity effects
in ionizing-radiation-induced … positioned chromosomes are more likely to be involved in …
in ionizing-radiation-induced … positioned chromosomes are more likely to be involved in …
Influence of nuclear geometry on the formation of genetic rearrangements in human cells
M Durante, D Pignalosa, JA Jansen… - Radiation …, 2010 - meridian.allenpress.com
… As a consequence, proximity of genes in the interphase … in human cells, at least when different
geometries are involved … to the absorbed dose when radiation-induced genetic damage is …
geometries are involved … to the absorbed dose when radiation-induced genetic damage is …
Interphase chromosome positioning affects the spectrum of radiation-induced chromosomal aberrations
JJWA Boei, J Fomina, F Darroudi… - Radiation …, 2006 - meridian.allenpress.com
… Indeed, the chromosomes involved in certain recurrent disease-specific chromosome
rearrangements were found in proximity in … Proximity of chromosomal loci that participate in …
rearrangements were found in proximity in … Proximity of chromosomal loci that participate in …