… A variety of regulatory requirements for ecotoxicity test data exist in the US and each of these
is … The requirements for large amounts of ecotoxicity data appears to have forced a practical …

… This approach uses existing data to determine threshold … number of animals used in regulatory
ecotoxicity testing. These … safety regulations; a move toward extrapolating the toxicity of …

… We hope that this will raise the issue in ecotoxicology and encourage … data, leading to
greater use and regulatory acceptance. We believe this is not only a scientifically valid approach …

… in conducting ecotoxicity tests. Ultimately, we gathered data from 14 OECD and 2 US EPA
… trout are used annually in relation to two key Canadian regulations governing effluent …

… , IMPACT 2002 and USES-LCA, and a systematic approach was developed to compare …
and/or estimate chemical properties and toxicity data, we focused our effort on identifying and …

… regulators to address important open questions of toxicology such as species-specific toxicity,
mixture toxicity, … , the respective data can already be used to support regulatory decisions. …

… of toxicity testing data is available; eg, 890,909 ecotoxicity test records for 11,320 chemicals
in the Ecotox database (US EPA, … perspectives of the same exposure-based toxicity testing …

… statistical method used in experimental toxicity, null hypotheses … standard regulatory toxicity
testing). They provide a seemingly consistent approach to the optimal analysis of real data in …

… In the present review, we critically survey the use of sediment toxicity testing in international
… from known toxicity data for a different species. While the ACR approach has been used for …

… toxicity, ecotoxicity and environment (CSTEE) has identified the requirement for a practical
approach in obtaining data … -government regulatory authorities to recommend the application …