… Tachykinin antagonists may represent useful pharmacological tools to characterize …
tachykinin receptors and to define better the role of these neuropeptides in central cardiovascular …

… and circulatory effects of three tachykinins detected in mammalian … Receptors for mammalian
tachykinins on isolated smooth … Responses of the rat cardiovascular system to substance P, …

… ) genes control the synthesis of tachykinin peptides [ 131. While … mechanisms, the two
tachykinin genes generate a family of … The poor selectivity shown by naturally occurring …

… in mammals, and tachykinin peptides were identified and … SP and other tachykinins in the
central nervous system (CNS) … of two other mammalian tachykinins, namely neurokinin A (NKA)…

… ), in addition to a robust tachykinin NK 2 receptor-mediated contraction, tachykinins also
cause contraction via tachykinin NK 1 receptor stimulation. The tachykinin NK 1 -mediated …

… tachykinins have physiologic/endocrine roles in the periphery. In the present study we report
a fundamental new function for tachykinins … We demonstrate the presence of the tachykinin …

… In summary, it is not unimaginable to explain the pharmacology of the new tachykinins within
the context of the three existing tachykinin receptors. Ultimately, only, histological analysis …

… Although the NTS appears to possess multiple tachykinin … of tachykinin receptors in the
NTS of the urethane-anaesthetized rat in an attempt to determine the involvement of tachykinin …

… NKB is the only tachykinin peptide produced from the NKB gene. These Several tachykinin
genes, with … , generate substantial diversity in the tachykinin peptides which can be produced. …

… and rainbow trout tachykinins, but rather true species variations because mammalian
tachykinins produce almost identical responses as rainbow trout tachykinins in the present study. …