… The role of CD40/CD40 ligand (CD40L) in atherothrombosis is now widely … linking the
CD40/CD40L system and the soluble form of CD40 ligand (sCD40L) with atherothrombosis are …

… vascular complications of diabetes and atherothrombosis, and in immunological diseases.
We also discuss a model of ROS-mediated amplification of inflammation in vascular cells. …

… CD40L axis to be a major player in immune and inflammatory events at large. In addition,
more recently, … If these advanced lesions are ruptured, an atherothrombotic event is triggered. …

… (MCP-1) and CD40/CD40 ligand (CD40L) interaction among platelets and endothelial cells,
where they trigger, modulate, or abate inflammatory mechanisms, especially in patients with …

Disrupting the CD40-CD40L co-stimulatory pathway reduces atherosclerosis and induces a
stable atherosclerotic plaque phenotype that is low in inflammation and high in fibrosis. …

… CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple
sclerosis. Proc Natl Acad Sci USA (1996) 93(6):2499–504. doi:10.1073/pnas.93.6.2499 …

The binding of CD40 ligand (CD40L) to CD40 stimulates inflammatory processes including
the release of proinflammatory cytokines and the expression of adhesion molecules implying …

… a chronic inflammatory disease in which both lipid and inflammatory pathways intertwine in
a complex network. Several decades ago, evidence surfaced associating inflammatory cells …

… to the pathophysiology of atherosclerosis and atherothrombosis. Indeed, sCD40L has …
platelet-leucocyte conjugation that may lead to atherothrombosis. It has even been suggested that …

… The role of CD40/CD40 ligand (CD40L) interactions in atherothrombosis, in the response
of the immune system to pathogens and in thrombosis is now widely accepted. A role for CD40…