… accumulation of amyloid β-peptide (Aβ) and neurofibrillary pathologies, and … The 3xTgAD
mouse model was used to test the hypothesis that a ketone ester–based diet can ameliorate …

… , diazoxide, a K ATP channel activator, reduced tau pathology and improved memory compared
to 3xTg-AD … in APP/PSI mice (in another mouse model of AD) [52]. In the present study, a …

… (10 μM), a K ATP channel inhibitor. The cells were then … mitoK ATP channel opener
diazoxide alleviated molecular, … linarin through activation of the PI3K/Akt pathway in amyloid-β-…

… AD mice early in the disease process cannot only improve … KATP channel activator diazoxide
ameliorates amyloid-beta and tau pathologies and improves memory in the 3xTgAD mouse …

… We also found that light therapy improved mitoBK Ca -β2 … avoidance test demonstrated
memory impairment in Aβ … Furthermore, it has been reported that activation of the BK Ca channel …

… protective effects of K ATP channel opener nicorandil against … The neuroprotective effects
of mitoK ATP opener diazoxide … diazoxide may therefore reduce Aβ production in 3xTgAD …

… ameliorate Aβ pathology and/or cognitive deficits in a mouse … not ameliorate spatial learning
and memory deficits in the AD … not improve cognition in APP/PS1 mice with Aβ pathology in …

… the most commonly used animal models to test memory. MWM … K ATP channel modulators
reduce infarct volumes, improved … provide benefits in VaD via ameliorating various behavioral, …

… AβPPxPS1, and 3xTg-AD transgenic mice models, found that … For example, inhibition of
tau kinases and/or activation of … p-tau- PROTACs to reduce p-tau toxicity and improve the …

… We also show that diazoxide (Dz), a K ATP channel agonist … ,17 , improved amyloid pathology
and memory impairment in … an AD mouse model and in postmortem brain of patients with …