… Biochemical studies revealed that Microphthalmia transcription factor protein (Mitf) binds …
enzyme gene expression through a signaling cascade that stimulates expression of Mitf …

… The first mouse microphthalmia transcription factor (Mitf ) mutation was discovered over 60
… (bHLH-Zip) transcription factors. Like Myc, Mitf regulates gene expression by binding to DNA …

… Microphthalmia-associated transcription factor (MITF) was initially shown to play a key
role in melanocyte differentiation through the direct transcriptional control of TYROSINASE, …

… factor-1 (LEF-1)/TCF transcription factors, containing a high-mobility-group domain (27, 28).
Thus, the LEF-1/TCF transcription factors … MITF-M expression through the functional LEF-1-…

… of transcription factors by signal transduction pathways acting to coordinate the transcriptional
… by the action of relatively few transcription factors expressed in a cell-type specific or …

… The protein encoded by the Microphthalmia gene (MITF) is a transcription factor essential
for the development and survival of melanocytes. It serves as a master regulator in modulating …

… The opportunity to examine structure/function rela tionships for transcription factor mutations
coordinately in vitro and in mice has rarely been possible. The mul titude of mi mouse …

Commitment to the melanocyte lineage is characterized by the onset of expression of the
microphthalmia-associated transcription factor (Mitf). This transcription factor plays a …

… Microphthalmia-associated transcription factor (MITF) regulates the differentiation and … is
also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. …

… The microphthalmia (MiT) subfamily of transcription factors includes TFE3, TFEB, TFEC, and
… by the rearrangement of the MiT transcription factors TFE3 and TFEB, respectively. Recent …