Prescribing amiodarone: an evidence-based review of clinical indications

P Vassallo, RG Trohman - Jama, 2007 - jamanetwork.com
… role for prophylactic amiodarone is in the perioperative period of cardiac surgery. Amiodarone
may be … However, amiodarone has a number of serious adverse effects, including corneal …

Simvastatin–amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity

B Ricaurte, A Guirguis, HC Taylor… - Annals of …, 2006 - journals.sagepub.com
Objective: To describe the fifth reported instance, as of February 15, 2006, of a severe
interaction between simvastatin and amiodarone and hypothesize inhibition of CYP3A4 as the …

S3881 A Case of Amiodarone-induced Noncirrhotic Hyperammonemia in the Absence of Liver Disease

J Ravilla, F Heis, S Taj, H Sanekommu… - Official journal of the …, 2023 - journals.lww.com
… levels without signs of cirrhosis as in our patient … amiodarone. Case Description/Methods:
A 74-year-old woman with medical history of non-ischemic cardiomyopathy, VT on amiodarone

Examining the safety of amiodarone

P Santangeli, L Di Biase, JD Burkhardt… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Amiodarone is the most widely used … the published evidence on amiodarone
versus placebo to … Expert opinion: Amiodarone is effective for both the acute conversion of …

Increased hepatic density and phospholipidosis due to amiodarone

IS Goldman, ML Winkler, SE Raper… - American journal of …, 1985 - Am Roentgen Ray Soc
Amiodarone is an amphiphilic iodinated compound that is … toxicity, a patient receiving
amiodarone was noted to have an … Six additional patients who were receiving amiodarone were …

Amiodarone-a 'broad spectrum'antiarrhythmic drug

SR Punnam, SK Goyal, VPK Kotaru… - … Current Drug Targets …, 2010 - ingentaconnect.com
… available regarding dosage adjustment in liver disease, although … liver disease as the drug
is extensively metabolized in the liver [13]. The therapeutic plasma range of amiodarone and …

Amiodarone: review of pulmonary effects and toxicity

SA Papiris, C Triantafillidou, L Kolilekas, D Markoulaki… - Drug safety, 2010 - Springer
… Fatal complications of amiodarone include ARDS, pulmonary fibrosis, cirrhosis and brady-…
seems to increase the risk of amiodarone lung toxicity and that amiodarone lung toxicity is less …

[HTML][HTML] Immediate oral amiodarone re-challenge following the development of parenteral-induced acute liver toxicity

J Offenbacher, F Kazi, N Chen… - World Journal of …, 2021 - ncbi.nlm.nih.gov
… central antiarrhythmic agent, amiodarone’s significant toxicity … similar to that of alcohol-induced
liver disease.[6, 7] Although … secondary to the IV infusions of amiodarone.[9] Unlike the …

[PDF][PDF] Amiodarone induced liver cirrhosis. Report of two cases

M Atiq, JC Davis, LW Lamps, SS Beland… - J Gastrointestin Liver …, 2009 - researchgate.net
Amiodarone is used commonly in patients with cardiac diseases. … liver cirrhosis secondary
to amiodarone therapy. We present two cases of liver cirrhosis in patients taking amiodarone. …

Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells

S Anthérieu, A Rogue, B Fromenty, A Guillouzo… - Hepatology, 2011 - journals.lww.com
… Our results show that amiodarone causes phospholipidosis after short-term treatment and,
like tetracycline, induces vesicular steatosis after repeat exposure in HepaRG cells. These …