A blastic plasmacytoid dendritic cell neoplasm-like phenotype identifies a subgroup of npm1-mutated acute myeloid leukemia patients with worse prognosis
… A blastic plasmacytoid dendritic cell neoplasm-like phenotype identifies a subgroup of
npm1-mutated acute myeloid leukemia patients with worse prognosis … Dendritic Cells /
pathology* … Phenotype …
npm1-mutated acute myeloid leukemia patients with worse prognosis … Dendritic Cells /
pathology* … Phenotype …
[HTML][HTML] A blastic plasmacytoid dendritic cell neoplasm-like phenotype identifies a subgroup of npm1-mutated aml patients with worse prognosis while has not …
Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) are a very rare group of
diseases included by WHO 2016 classification among the myeloid neoplasms and usually
display an aggressive course with dismal outcome. BPDCN are characterized by a recurrent
phenotype (CD45low/CD34-/CD56+/CD4+/CD123+), in the absence of other lineage
differentiation markers. Our group recently reported that a subset of patients diagnosed with
AML with NPM1-mutation carrying co-expression of CD123, CD56 and CD4, a “BPDCN-like” …
diseases included by WHO 2016 classification among the myeloid neoplasms and usually
display an aggressive course with dismal outcome. BPDCN are characterized by a recurrent
phenotype (CD45low/CD34-/CD56+/CD4+/CD123+), in the absence of other lineage
differentiation markers. Our group recently reported that a subset of patients diagnosed with
AML with NPM1-mutation carrying co-expression of CD123, CD56 and CD4, a “BPDCN-like” …