A cryptic insertion (17; 15) on both chromosomes 17 with lack of PML–RARA expression in a case of atypical acute promyelocytic leukemia

J Tchinda, S Volpert, R Liersch, M Zühlsdorf, H Serve… - Leukemia, 2004 - nature.com
… It is important to confirm a cryptic insertion or translocation … All APL with cryptic insertions
(15;17) or (17;15) evidenced … case has been described with ins(17;15) expressing RARα–PML …

Recurrent locus-specific mutation resulting from a cryptic ectopic insertion in Neurospora

DD Perkins, M Freitag, VC Pollard, LA Bailey-Shrode… - Genetics, 2007 - academic.oup.com
… copy of cya-8 + that was inserted ectopically at eas when the UCLA191 mutation occurred. As
… These findings support a model in which an ectopic insertion that created a mutation at the …

Cryptic insertion and translocation or nondividing leukemic cells disclosed by FISH analysis in infant acute leukemia with discrepant molecular and cytogenetic …

N Watanabe, H Kobayashi, O Ichiji, MA Yoshida… - Leukemia, 2003 - nature.com
… in five patients, and cryptic insertion or translocation in another five… that were produced by
the cryptic rearrangements in four of the … Karyotypes from 17 patients with AML were published …

The genetic characterization of acute promyelocytic leukemia with cryptic t (15; 17) including a new recurrent additional cytogenetic abnormality i (17)(q10)

M Kim, J Lim, Y Kim, K Han, DH Lee, NG Chung, B Cho… - Leukemia, 2008 - nature.com
… A cryptic insertion (17;15) on both chromosomes 17 with lack of PML-RARA expression
in a case of atypical acute promyelocytic leukemia. Leukemia 2004; 18: 183–186. 5 Lee G, …

A paediatric acute promyelocytic leukaemia patient harbouring a cryptic pml-rara insertion due to a complex structural chromosome 17 rearrangement

R El-Hajj Ghaoui, L St Heaps, D Hung… - … and Genome Research, 2018 - karger.com
… 15;17)(q24.1;q21.1) translocation but may also arise from complex or cryptic rearrangements…
We describe a cryptic PML-RARA fusion within a novel chromosome 17 rearrangement. We …

Acute promyelocytic leukemia with a cryptic insertion of RARA into TBL1XR1

T Osumi, A Watanabe, K Okamura… - Genes …, 2019 - Wiley Online Library
… structure; RARA on chromosome 17 had a 12-kbp deletion, of which a small front part was
inserted into chromosome X and the major part was inserted within TBL1XR1 between exons …

Cryptic t (4; 11) encoding MLL-AF4 due to insertion of 5′ MLL sequences in chromosome 4

A Von Bergh, P Gargallo, B De Prijck, H Vranckx… - Leukemia, 2001 - nature.com
… , we show the existence of a cryptic t(4;11) translocation, resulting from a double mono-allelic
breakpoint and insertion of the 5′ MLL … translocations, t(15;17) and t(8;21) in AML27…

[HTML][HTML] Cryptic MYC insertions in Burkitt lymphoma: New data and a review of the literature

R Woroniecka, G Rymkiewicz, LM Szafron, K Blachnio… - Plos one, 2022 - journals.plos.org
… On the other hand, we demonstrated that nearly 17% of the MYC-negative suspBL had
cryptic MYC insertions. As we have previously emphasized, MYC negativity defined by using …

Cryptic insertion into 11q23 of MLLT10 not involved in t (1; 15; 11; 10)(p36; q11; q23; q24) in infant acute biphenotypic leukemia

K Matsuda, M Tanaka, S Araki, R Yanagisawa… - Cancer genetics and …, 2009 - Elsevier
… duplication and exon 17 of the Fms-related tyrosine kinase 3 (FLT3) gene, exons 8–11, 17,
and 18 … Accordingly, we could not determine whether part of MLLT10 was inserted into RP11-…

Cytogenetically cryptic insertion of PML segment into RARA on chromosome 17q resulting PML-RARA fusion in acute promyelocytic leukemia

TF Burns, EY Loo, EM Bengtson, L Bao - Annals of Hematology, 2019 - Springer
… 15;17) that produces two fusion products, PML-RARA and its reciprocal fusion RARA-PML,
the interstitial insertion … features comparable with classic t(15;17)-APL supports the notion that …