A myriad of pathways to NASH
S Larrain, ME Rinella - Clinics in liver disease, 2012 - Elsevier
… to the NASH population, we should consider what the appropriate therapy is for each
specific patient with NASH. The most effective pharmacologic treatments for NASH to date have …
specific patient with NASH. The most effective pharmacologic treatments for NASH to date have …
Multi-drug approaches to NASH: what's in the development pipeline?
MP Johnston, J Patel, CD Byrne - Expert Opinion on Investigational …, 2020 - Taylor & Francis
… there is a myriad of agents … NASH will become analogous to the treatment of hypertension;
it is very likely that multiple different classes of drugs targeting different mechanistic pathways …
it is very likely that multiple different classes of drugs targeting different mechanistic pathways …
Maladaptive regeneration—the reawakening of developmental pathways in NASH and fibrosis
… pathways and review the cell-autonomous and cell-non-autonomous mechanisms by which
developmental pathways … therapeutic implications of these data for NASH and liver fibrosis. …
developmental pathways … therapeutic implications of these data for NASH and liver fibrosis. …
[HTML][HTML] Recent insights into the multiple pathways driving non-alcoholic steatohepatitis-derived hepatocellular carcinoma
K Takakura, T Oikawa, M Nakano, C Saeki… - Frontiers in …, 2019 - frontiersin.org
… myriad landmark discoveries of recent research into the pathogenic processes underlying
NASH-… related molecules in the inflammatory pathways underlying NASH-HCC progression, …
NASH-… related molecules in the inflammatory pathways underlying NASH-HCC progression, …
[HTML][HTML] Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
W Peverill, LW Powell, R Skoien - International journal of molecular …, 2014 - mdpi.com
… but potentially multiple fibrogenic pathways exist in NASH, with … of NASH are aimed at the
myriad of inter-cellular mechanisms that have been implicated in the pathogenesis of NASH. …
myriad of inter-cellular mechanisms that have been implicated in the pathogenesis of NASH. …
Pharmacotherapy for NASH: current and emerging
MA Konerman, JC Jones, SA Harrison - Journal of hepatology, 2018 - Elsevier
… NAFLD and NASH are complex and reflected by the myriad of … In NASH, the developmental
pathway for therapeutic agents … as paediatric drug development pathways differ significantly. …
pathway for therapeutic agents … as paediatric drug development pathways differ significantly. …
Clinical care pathway for the risk stratification and management of patients with nonalcoholic fatty liver disease
F Kanwal, JH Shubrook, LA Adams, K Pfotenhauer… - Gastroenterology, 2021 - Elsevier
… often inconsistent care processes characterizing current approaches to NAFLD/NASH. The
NAFLD/NASH Clinical Care Pathway presented in this article was assembled by an expert …
NAFLD/NASH Clinical Care Pathway presented in this article was assembled by an expert …
Innate immunity and inflammation in NAFLD/NASH
M Arrese, D Cabrera, AM Kalergis… - Digestive diseases and …, 2016 - Springer
… in NASH and the predominant cell death pathway in this disease [12, 22]. Apoptosis is initiated
by either membrane receptors (extrinsic pathway… consisting of a myriad of signals evoking …
by either membrane receptors (extrinsic pathway… consisting of a myriad of signals evoking …
[HTML][HTML] The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis
N Méndez-Sánchez, A Valencia-Rodríguez… - Annals of …, 2020 - ncbi.nlm.nih.gov
… through the recognition of a myriad of danger signs known as … plays an important role in
NASH progression. Recent studies … In addition to these pathways, patients with NASH reveal …
NASH progression. Recent studies … In addition to these pathways, patients with NASH reveal …
[HTML][HTML] From NASH to diabetes and from diabetes to NASH: mechanisms and treatment options
A Gastaldelli, K Cusi - JHEP reports, 2019 - Elsevier
… the impairment of many metabolic pathways, including decreased … for the treatment of NASH,
we discuss pharmacological … They also have a myriad of other beneficial metabolic effects, …
we discuss pharmacological … They also have a myriad of other beneficial metabolic effects, …