A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration

KS Alharbi, WH Almalki, SI Alzarea, I Kazmi… - Chemico-Biological …, 2022 - Elsevier
Cardiomyocyte regeneration following cardiac damage is challenging to study because of
the inflammatory process, the multiplication of cells in the stroma, and the creation of scar
tissue. In addition to the initial damage, the subsequent decrease in cardiac myocytes adds
to heart failure. Piezo1 is remarkably understudied in the heart, which may be related to its
recent discovery. Despite this, Piezo1 is expressed in a variety of cardiovascular cell
populations, notably epithelial cells (EC), cardiac fibroblasts (CF), and cardiac myocytes …
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