A novel, extremely bioavailable cocrystal of pterostilbene
L Bofill, R Barbas, D de Sande… - Crystal Growth & …, 2021 - ACS Publications
Crystal Growth & Design, 2021•ACS Publications
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered
and characterized through experimental cocrystal screening. Among the coformers tested,
picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats,
which converts the new cocrystal into a very promising candidate for new formulations of
pterostilbene with improved performance.
and characterized through experimental cocrystal screening. Among the coformers tested,
picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats,
which converts the new cocrystal into a very promising candidate for new formulations of
pterostilbene with improved performance.
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
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