… model of bone cancer pain in the rat. Sprague–Dawley rats receiving intra-tibial injections of
syngeneic MRMT-1 rat … behavioural signs indicative of pain, including: mechanical allodynia…

… However, the role of glial cells in bone cancer pain is … rat model of bone cancer pain produced
by injecting AT-3.1 prostate cancer cells into the unilateral tibia of male Copenhagen rats. …

… of use of animal models of bone cancer pain, we conducted a systematic review and meta-analysis.
We excluded studies using models of metastatic cancer that did not report a pain-…

… This study described a modified rat model of bone cancer pain… including bone radiology,
bone histology, ambulatory pain, … The rats inoculated with carcinoma cells showed significant …

… of the affected bone. Thus animal models that mimic both bone tumor pain and remodeling
… Therefore studies in both mouse and rat models of bone cancer pain indicate that glial cell …

… propose in this animal model are based on clinical multimodal approaches and are intended
to optimize the research and development of therapeutic strategies for bone cancer pain. …

… Thus, using a well-characterized rat model, we … of bone cancer pain and to determine
whether diclofenac has direct effects on peripheral A-type K + channels and bone cancer pain. …

… In the present study, we examined the expression of P2X 3 receptors in DRG in a rat model
of bone cancer pain. Functional significance of altered P2X 3 receptors was investigated by …

… of the effects of acupuncture on such pain are not clear ( 19,20 ). The aim … bone cancer pain
in an established rat model, produced by injecting prostate cells into the tibia cavity of the rat, …

… destruction and the dorsal horn neurochemical markers all suggest that cancer-induced
bone pain is a unique pain state. Here we employ a rat model of cancer-induced bone pain, …