A review on Alzheimer's disease pathophysiology and its management: an update

A Kumar, A Singh - Pharmacological reports, 2015 - Elsevier
Alzheimer's disease acknowledged as progressive multifarious neurodegenerative disorder,
is the leading cause of dementia in late adult life. Pathologically it is characterized by
intracellular neurofibrillary tangles and extracellular amyloidal protein deposits contributing
to senile plaques. Over the last two decades, advances in the field of pathogenesis have
inspired the researchers for the investigation of novel pharmacological therapeutics
centered more towards the pathophysiological events of the disease. Currently available …
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