[HTML][HTML] Antimicrobial peptides in the battle against orthopedic implant-related infections: A review
Prevention of orthopedic implant-related infections is a major medical challenge, particularly
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current
therapies, based on antibiotic administration, have proven to be insufficient, and infection
prevalence may rise due to the dissemination of antibiotic resistance. Antimicrobial peptides
(AMPs) have attracted attention as promising substitutes of conventional antibiotics, owing to
their broad-spectrum of activity, high efficacy at very low concentrations, and, importantly …
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current
therapies, based on antibiotic administration, have proven to be insufficient, and infection
prevalence may rise due to the dissemination of antibiotic resistance. Antimicrobial peptides
(AMPs) have attracted attention as promising substitutes of conventional antibiotics, owing to
their broad-spectrum of activity, high efficacy at very low concentrations, and, importantly …
[PDF][PDF] Antimicrobial Pep-tides in the Battle against Orthopedic Implant-Related Infections: A Review. Pharmaceutics 2021, 13, 1918
B Costa, G Martínez-de-Tejada, PAC Gomes… - 2021 - academia.edu
Prevention of orthopedic implant-related infections is a major medical challenge, particularly
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current
therapies, based on antibiotic administration, have proven to be insufficient, and infection
prevalence may rise due to the dissemination of antibiotic resistance. Antimicrobial peptides
(AMPs) have attracted attention as promising substitutes of conventional antibiotics, owing to
their broad-spectrum of activity, high efficacy at very low concentrations, and, importantly …
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current
therapies, based on antibiotic administration, have proven to be insufficient, and infection
prevalence may rise due to the dissemination of antibiotic resistance. Antimicrobial peptides
(AMPs) have attracted attention as promising substitutes of conventional antibiotics, owing to
their broad-spectrum of activity, high efficacy at very low concentrations, and, importantly …
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