Tolnidamine (50 mg/kg body weight; twice a week; oral) was administered for 90 days to
adult male langur monkeys (Presbytis entellus entellus Dufresne) to assess its contraceptive
potential. Semen weight, volume, seminal fluid volume, colour, pH and libido remained
unchanged. Sperm motility, vitality and morphology were impaired with the advancement of
treatment. Sperm density reduced to severe oligospermia following 75–90 days of treatment.
Increased number of immature germ cells were also noticed. Resumption of changes to …