Biodistribution and first clinical results of 18F-SiFAlin-TATE PET: a novel 18F-labeled somatostatin analog for imaging of neuroendocrine tumors

H Ilhan, S Lindner, A Todica, CC Cyran, R Tiling… - European journal of …, 2020 - Springer
Abstract Introduction PET/CT using 68 Ga-labeled somatostatin analogs (SSA) targeting
somatostatin receptors (SSR) on the cell surface of well-differentiated neuroendocrine
tumors (NET) represents the clinical reference standard for imaging. However, economic
and logistic challenges of the 68 Ge/68 Ga generator-based approach have disadvantages
over 18 F-labeled compounds. Here, we present the first in-human data of 18 F-SiFA lin-
TATE, a novel 18 F-labeled, SSR-targeting peptide. The aim was to compare the intra …

Biodistribution and first clinical results of 18F-SiFAlin-TATE PET

H Ilhan, S Lindner, A Todica, CC Cyran, R Tiling… - 2020 - katalog.ub.uni-heidelberg.de
PET/CT using 68Ga-labeled somatostatin analogs (SSA) targeting somatostatin receptors
(SSR) on the cell surface of well-differentiated neuroendocrine tumors (NET) represents the
clinical reference standard for imaging. However, economic and logistic challenges of the
68Ge/68Ga generator-based approach have disadvantages over 18F-labeled compounds.
Here, we present the first in-human data of 18F-SiFAlin-TATE, a novel 18F-labeled, SSR-
targeting peptide. The aim was to compare the intra-individual biodistribution, tumor uptake …
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