[HTML][HTML] Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP)
LAE Hughes, CCJM Simons, PA van den Brandt… - PloS one, 2011 - journals.plos.org
Background We investigated how body size and physical activity influence the risk of the
CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Methods In the
Netherlands Cohort Study (n= 120,852), risk factors were self-reported at baseline in 1986.
After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP
status according to the Weisenberger markers was determined using methylation specific
PCR on DNA from paraffin embedded tumor tissue. Hazard rate ratios (HR) and 95 …
CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Methods In the
Netherlands Cohort Study (n= 120,852), risk factors were self-reported at baseline in 1986.
After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP
status according to the Weisenberger markers was determined using methylation specific
PCR on DNA from paraffin embedded tumor tissue. Hazard rate ratios (HR) and 95 …
[PDF][PDF] Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP)
R Brandt, AFPM de Goeij… - Energy balance …, 2013 - cris.maastrichtuniversity.nl
Background: We investigated how body size and physical activity influence the risk of the
CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Methods: In the
Netherlands Cohort Study (n= 120,852), risk factors were self-reported at baseline in 1986.
After 7.3 years of follow-up, 603 cases and 4,631 subcohort members were available. CIMP
status according to the Weisenberger markers was determined using methylationspecific
PCR on DNA from paraffin-embedded tumor tissue. Hazard rate ratios (HR) and 95 …
CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Methods: In the
Netherlands Cohort Study (n= 120,852), risk factors were self-reported at baseline in 1986.
After 7.3 years of follow-up, 603 cases and 4,631 subcohort members were available. CIMP
status according to the Weisenberger markers was determined using methylationspecific
PCR on DNA from paraffin-embedded tumor tissue. Hazard rate ratios (HR) and 95 …
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