CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2014 - Am Soc Clin Investig
… CXCL11 redirects the polarization of effector T cells into IL-10 hi Tr1 cells and suppresses
polarization of effector T cells into IL-10 hi Tr1 cells? Primary CD4 + T cells were obtained from …

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2018 - Am Soc Clin Investig
… Using GFP-expressing effector CD4 + T cells, we observed that successful therapy was …
cells at the autoimmune site. Finally, we showed that very low doses of CXCL11 rapidly suppress

The role of chemokines in adjusting the balance between CD4+ effector T cell subsets and FOXp3-negative regulatory T cells

N Karin, G Wildbaum - International immunopharmacology, 2015 - Elsevier
… These cells suppress the activities of effector T cells, and of inflammatory macrophages by …
of experimental autoimmune encephalomyelitis (EAE), a T cell mediated autoimmune disease …

[HTML][HTML] CXCR3 ligands in cancer and autoimmunity, chemoattraction of effector T cells, and beyond

N Karin - Frontiers in immunology, 2020 - frontiersin.org
… Based on their cytokine profile FOXp3-negative CD4+ T cellsautoimmune encephalomyelitis
(EAE), and adjuvant induced … derived cells that support tumor growth and suppress anti-…

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2017 - Am Soc Clin Investig
… Using GFP-expressing effector CD4 + T cells, we observed that successful therapy was …
cells at the autoimmune site. Finally, we showed that very low doses of CXCL11 rapidly suppress

Biased signaling pathways via CXCR3 control the development and function of CD4+ T cell subsets

N Karin, G Wildbaum, M Thelen - Journal of Leucocyte Biology, 2016 - academic.oup.com
… I diabetes and experimental autoimmune encephalomyelitis. Recently, we … -positive T cells
could be polarized from FOXP3-negative T cells (in vitro) … naturally occurring regulatory T cell

Chemokine responses and T cell recruitment in central nervous system alphaherpesvirus infections

L Lind - 2018 - gupea.ub.gu.se
… + T cells infiltrations of ganglia, by suppressing reactivation … We were also interested in
the role of regulatory T cells in the … few regulatory T cells in the CNS of mice with HSV-2-induced

[PDF][PDF] Type I interferon therapy limits CNS autoimmunity by inhibiting CXCR3-mediated trafficking of pathogenic effector T cells

W Wang, WP Chong, C Li, Z Chen, S Wu, H Zhou… - Cell reports, 2019 - cell.com
autoimmune encephalomyelitis (EAE) have been found effective, we set out to examine the
modulatory effects of type I IFNs on the disease pathogenesis of autoimmunesuppresses

[HTML][HTML] The role of chemokines in shaping the balance between CD4+ T cell subsets and its therapeutic implications in autoimmune and cancer diseases

N Karin, G Wildbaum - Frontiers in immunology, 2015 - frontiersin.org
… the polarization of effector and regulatory T cell subset and the … -12 inhibits experimental
autoimmune encephalomyelitis (EAE… T cells could be polarized from FOXP3-negative T cells (in …

CCR8+FOXp3+ Treg cells as master drivers of immune regulation

Y Barsheshet, G Wildbaum, E Levy… - Proceedings of the …, 2017 - National Acad Sciences
… identifies CCR8 + regulatory T cells (T reg cells) as drivers of … The suppression of ongoing
autoimmunity by a stabilized … sclerosis [experimental autoimmune encephalomyelitis, (EAE)] …