Vascular smooth muscle phenotypic diversity and function
SA Fisher - Physiological genomics, 2010 - journals.physiology.org
… Of note, the cGK target the IP3 receptor-associated gated protein (IRAG = MRVI1) has not
been reported to be differentially expressed across smooth muscle tissues (86). …
been reported to be differentially expressed across smooth muscle tissues (86). …
Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and in stent stenosis in humans
QJ Zhang, M Goddard, C Shanahan… - … , and vascular biology, 2002 - Am Heart Assoc
… sought to identify differentially expressed genes in human in … Target gene fragments were
cloned into a T7/SP6 promoter-… VSMCs exhibit a stable phenotype, intermediate between …
cloned into a T7/SP6 promoter-… VSMCs exhibit a stable phenotype, intermediate between …
Smooth muscle cell heterogeneity: patterns of gene expression in vascular smooth muscle cells in vitro and in vivo
CM Shanahan, PL Weissberg - … , thrombosis, and vascular biology, 1998 - Am Heart Assoc
… of VSMC clones with apparently stable phenotypes in vitro. … gene expression that characterize
the phenotypic changes that occur in vivo and to determine the mechanisms that regulate …
the phenotypic changes that occur in vivo and to determine the mechanisms that regulate …
Myosin gene expression and cell phenotypes in vascular smooth muscle during development, in experimental models, and in vascular disease
S Sartore, A Chiavegato, R Franch… - … , and vascular biology, 1997 - Am Heart Assoc
… -MyHC isoforms are differentially expressed in SMCs during physiological and pathological
… from cloning of adult SM tissue display features in common with developing and “phenotype-…
… from cloning of adult SM tissue display features in common with developing and “phenotype-…
Innate diversity of adult human arterial smooth muscle cells: cloning of distinct subtypes from the internal thoracic artery
S Li, YS Fan, LH Chow, C Van Den Diepstraten… - Circulation …, 2001 - Am Heart Assoc
… Smooth muscle cells (SMCs) in the adult artery wall can manifest a diversity of phenotypes.
… Some SMC subsets have been shown to differentially respond to mitogenic factors, …
… Some SMC subsets have been shown to differentially respond to mitogenic factors, …
Evidence from a novel human cell clone that adult vascular smooth muscle cells can convert reversibly between noncontractile and contractile phenotypes
S Li, S Sims, Y Jiao, LH Chow, JG Pickering - Circulation research, 1999 - Am Heart Assoc
… capacity for bidirectional modulation of phenotype. However, this … cloning adult SMCs from
human internal thoracic artery. One clone, HITB5, expressed smooth muscle α-actin, smooth …
human internal thoracic artery. One clone, HITB5, expressed smooth muscle α-actin, smooth …
Molecular control of vascular smooth muscle cell differentiation
GK Owens - Acta physiologica scandinavica, 1998 - Wiley Online Library
… Stretch affects phenotype and proliferation of vascular smooth muscle cells. MoL CellBiochem
… Molecular cloning and sequence analysis of smooth muscle calponin. J Bioi Chem 266, …
… Molecular cloning and sequence analysis of smooth muscle calponin. J Bioi Chem 266, …
Regulation and characteristics of vascular smooth muscle cell phenotypic diversity
SSM Rensen, P Doevendans, G Van Eys - Netherlands Heart Journal, 2007 - Springer
… PDGF-B drove spindle-shaped SMC clones towards the rhomboid phenotype. Concomitantly,
… Many of these differentially expressed genes code for ECM or cytoskeletal proteins, and …
… Many of these differentially expressed genes code for ECM or cytoskeletal proteins, and …
Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells.
CM Shanahan, PL Weissberg, JC Metcalfe - Circulation research, 1993 - Am Heart Assoc
… It is uncertain to what extent the phenotypic changes that occur in culture reflect the … in
transcript size for matrix Gla protein occurred in cultured vascular smooth muscle cells. Clones that …
transcript size for matrix Gla protein occurred in cultured vascular smooth muscle cells. Clones that …
… of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic …
RC Chambers, P Leoni, N Kaminski, GJ Laurent… - The American journal of …, 2003 - Elsevier
… used as a phenotypic marker of the … synthetic phenotype for vascular smooth muscle cells.
Of interest, maximal expression of most of these smooth-muscle cell phenotypic marker genes …
Of interest, maximal expression of most of these smooth-muscle cell phenotypic marker genes …