Combined hyperthermia and immunotherapy treatment of multiple pulmonary metastases in mice
ED Strauch, DF Fabian, J Turner, AT Lefor - Surgical Oncology, 1994 - Elsevier
The combination of immunotherapy and hyperthermia results in a greater reduction in
tumour growth compared to either therapy used alone in a murine subcutaneous tumour
model. To evaluate this combination further we tested it in a murine pulmonary metastasis
model. Mice were given 5× 10 5 MCA-105 sarcoma cells on day 0 intravenously resulting in
the formation of pulmonary metastases. Mice were treated with local hyperthermia to the left
hemithorax with a transcutaneous microwave applicator or with whole-body hyperthermia to …
tumour growth compared to either therapy used alone in a murine subcutaneous tumour
model. To evaluate this combination further we tested it in a murine pulmonary metastasis
model. Mice were given 5× 10 5 MCA-105 sarcoma cells on day 0 intravenously resulting in
the formation of pulmonary metastases. Mice were treated with local hyperthermia to the left
hemithorax with a transcutaneous microwave applicator or with whole-body hyperthermia to …
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